Category Archives: Co-infections

Incidence of HIV-associated tuberculosis among individuals taking combination antiretroviral therapy: A systematic review and meta-analysis.

2014

BACKGROUND: Knowledge of tuberculosis incidence and associated factors is required for the development and evaluation of strategies to reduce the burden of HIV-associated tuberculosis. METHODS: Systematic literature review and meta-analysis...

Comparing research investment to United Kingdom institutions and published outputs for tuberculosis, HIV and malaria: A systematic analysis across 1997–2013

2015

BACKGROUND: The “Unfinished Agenda” of infectious diseases is of great importance to policymakers and research funding agencies that require ongoing research evidence on their effective management. Journal publications help effectively...

A systematic review of the effects of visual inspection with acetic acid, cryotherapy, and loop electrosurgical excision procedures for cervical dysplasia in HIV-infected women in low- and middle-income countries

2015

BACKGROUND: Cervical cancer, almost all of which is caused by human papillomavirus, accounts for 12% of female cancers worldwide and is more common among HIV-infected women. Nine of 10 deaths...

Prevalence of HIV and hepatitis B virus co-infection in sub-Saharan Africa and the potential impact and program feasibility of hepatitis B surface antigen screening in resource-limited settings

2015

BACKGROUND: Screening people living with HIV for hepatitis B virus (HBV) co-infection is recommended in resource-rich settings to optimize HIV antiretroviral therapy (ART) and mitigate HBV-related liver disease. This review...

Antiretroviral therapy for children in resource-limited settings: Current regimens and the role of newer agents

2011

WHO antiretroviral treatment guidelines for HIV-infected children have influenced the design of treatment programmes in resource-limited settings. This review analyses the latest WHO first- and second-line regimen recommendations. The recommendation...

A systematic review of risk factors for death in adults during and after tuberculosis treatment

2011

BACKGROUND: Despite effective anti-tuberculosis chemotherapy, case-fatality rates of up to 25% are described in both industrialised and resource-poor settings. An understanding of the factors predisposing to poor outcome may allow...

TB and HIV in the Central African region: Current knowledge and knowledge gaps

2014

PURPOSE: Reliable and comprehensive data on the HIV/AIDS and TB co-pandemics from Central Africa remain scarce. This systematic review provides a comprehensive overview on current and past research activities in...

Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive adults

2010

BACKGROUND: According to consensus, initiation of therapy is best based on CD4 cell count, a marker of immune status, rather than on viral load, a marker of virologic replication. For...

The effect of tuberculosis on mortality in HIV positive people: A meta-analysis

2010

Tuberculosis is a leading cause of death in people living with HIV (PLWH). We conducted a meta analysis to assess the effect of tuberculosis on mortality in people living with...

Heterosexual transmission of HIV in China: A systematic review of behavioral studies in the past two decades

2005

Objective: The objective of this study was to address the role of heterosexual transmission of HIV in China. Goal: The goal of this study was to explore the prevalence of...

Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV

2005

BACKGROUND: Cryptococcal disease is an opportunistic infection that causes significant morbidity and mortality in adults with HIV. Primary prophylaxis with antifungal interventions may decrease cryptococcal disease incidence and associated mortality....

Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States

2002

A meta-analysis was performed to examine the effects of 14 behavioral and social interventions for heterosexual adults on their adoption of safer sex behaviors or incidence of sexually transmitted diseases...

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