Category Archives: Co-infections

Burden of tuberculosis in underserved populations in South Africa: A systematic review and meta-analysis

2024

Identifying case-finding strategies to reduce tuberculosis (TB) incidence in high-burden countries requires better knowledge of the disease burden in key contributing populations and settings. To inform South Africa’s National Tuberculosis...

Innovative pre-exposure prophylaxis interventions among adolescent girls and young women during COVID-19 lockdown period in sub-Saharan Africa: A systematic review

2024

Adolescent girls and young women are key, and priority populations impacted by a higher risk of acquiring human immunodeficiency virus. In 2015, pre-exposure prophylaxis was introduced as a biomedical human...

Respiratory syncytial virus among people living with HIV: Is there a case for rolling out prophylaxis? A viewpoint based on a systematic review

2024

Respiratory Syncytial Virus (RSV) is responsible for a considerable burden of respiratory disease among children and older adults. Several prophylactic strategies have recently been introduced. We review the available evidence...

Exploring facilitators and barriers to STD/STI/HIV self-testing among college students in the United States: A scoping review

2024

Background: HIV affects 1.2 million Americans, with 20% of new diagnoses being 13 to 24-year-olds. Young adult college students are more likely than the general population of 18 to 24-year-olds in...

A systematic review and meta-analysis of the impact of the COVID-19 pandemic on access to HIV pre-exposure prophylaxis: Lessons for future public health crises

2024

BACKGROUND: The World Health Organization is committed to strengthening access to pre-exposure prophylaxis (PrEP) for HIV prevention and its integration into primary care services. Unfortunately, the COVID-19 pandemic has disrupted...

High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: A systematic review and meta-analysis

2024

Purpose: People living with HIV (PWH) experience a disproportionate burden of sexually transmitted infections (STIs), leading to more severe health outcomes and increasing the risk of HIV transmission. The presence of...

Doxycycline post-exposure prophylaxis for bacterial sexually transmitted infections: The current landscape and future directions

2024

PURPOSE OF REVIEW: The incidence of bacterial sexually transmitted infections (STI) continues to rise particularly among men who have sex with men (MSM). Doxycycline post-exposure prophylaxis (doxy-PEP) has emerged as...

A systematic review of factors associated with COVID-19 vaccine uptake, hesitancy, and acceptability among adults with HIV: Implications for integrating COVID-19 immunization into HIV care

2024

The COVID-19 virus, once a public health emergency, is now endemic. Immunization remains an important measure for mitigating high levels of disease, morbidity, and mortality related to COVID-19 infection. People...

Prevalence of Giardia duodenalis among African children: A systematic review and meta-analysis

2024

BACKGROUND: Giardia duodenalis (G. duodenalis) is one of the major causes of diarrhea among children. We performed a systematic review and meta-analysis to assess the prevalence of G. duodenalis and...

Effectiveness of MenB-4C vaccine against gonorrhea: A systematic review and meta-analysis

2024

Introduction: There is no licensed vaccine against gonorrhea but Neisseria meningitidis serogroup B outer membrane vesicle-based vaccines, like MenB-4C, may offer cross-protection against gonorrhea. This systematic review and meta-analysis synthesized...

Prevalence of co-trimoxazole resistance among HIV-infected individuals in Ethiopia: A systematic review and meta-analysis

2024

Background Co-trimoxazole is used as a prophylaxis for human immunodeficiency virus (HIV) patients to prevent opportunistic infections. Its widespread use results in the emergence of co-trimoxazole resistance, which is a...

Overview of hepatitis B vaccine non-response and associated B cell amnesia: A scoping review

2024

BACKGROUND: The advent of the hepatitis B vaccine has achieved tremendous success in eradicating and reducing the burden of hepatitis B infection, which is the main culprit for hepatocellular carcinoma-one...

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