Category Archives: Co-infections

Suppression of HBV by tenofovir in HBV/HIV coinfected patients: A systematic review and meta-analysis.

2013

BACKGROUND: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available...

Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis

2010

The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...

Syphilis in drug users in low and middle income countries

2010

BACKGROUND: Genital ulcer disease (GUD), including syphilis, is an important cause of morbidity in low and middle income (LMI) countries and syphilis transmission is associated with HIV transmission. METHODS: We...

Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts

2011

There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...

Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis

2014

BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...

Pulmonary tuberculosis in severely-malnourished or HIV-infected children with pneumonia: A review

2013

Presentation of pulmonary tuberculosis (PTB) as acute pneumonia in severely-malnourished and HIV-positive children has received very little attention, although this is very important in the management of pneumonia in children...

Opiate substitution treatment and HIV transmission in people who inject drugs: Systematic review and meta-analysis

2012

Objective To quantify the effect of opiate substitution treatment in relation to HIV transmission among people who inject drugs. Design Systematic review and meta-analysis of prospective published and unpublished observational...

Evidence behind the WHO guidelines: hospital care for children: What is the evidence that BCG vaccination should not be used in HIV-infected children?

2009

The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines,...

Population-based interventions for reducing sexually transmitted infections, including HIV infection

2004

BACKGROUND: Sexually transmitted infections (STI) are common in developing countries. The World Health Organisation (WHO) estimates that in 1999, 340 million new cases of syphilis, gonorrhoea, chlamydial infection and trichomoniasis...

Co-infection Trypanosoma cruzi/HIV: Systematic review (1980-2010)

2011

Introduction: The co-infection Trypanosoma cruzi/HIV has been described as a clinical event of great relevance. The objective of this study was to describe clinical and epidemiological aspects published in literature....

A systematic review and meta-analysis of risk factors for sexual transmission of HIV in India

2012

Background Approximately 2.4 million people are living with HIV in India. This large disease burden, and potential for epidemic spread in some areas, demands a full understanding of transmission in...

Does trimethoprim-sulfamethoxazole prophylaxis for HIV induce bacterial resistance to other antibiotic classes? Results of a systematic review

2011

BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis has long been recommended for immunosuppressed HIV-infected adults and children born to HIV-infected women. Despite this, many resource-limited countries have not implemented this recommendation, partly because...

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