Category Archives: Co-infections
Association between the CD209 promoter -336A/G polymorphism and susceptibility to tuberculosis: A meta-analysis
Background and objective: Dendritic cell-specific intracellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN), encoded by the CD209 gene, is a major Mycobacterium tuberculosis receptor on human dendritic cells. The potentially functional -336A/G...
Short-course therapy with rifampin plus isoniazid, compared with standard therapy with isoniazid, for latent tuberculosis infection: A meta-analysis
Background. A major difficulty associated with the use of standard therapy with isoniazid for latent tuberculosis infection is poor patient adherence to therapy because of the prolonged course required. Shorter...
Human immunodeficiency virus associated tuberculosis more often due to recent infection than reactivation of latent infection
BACKGROUND: It is unclear whether human immunodeficiency virus (HIV) increases the risk of tuberculosis (TB) mainly through reactivation or following recent Mycobacterium tuberculosis (re)infection. Within a DNA fingerprint-defined cluster of...
Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: A systematic review
HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated...
Predictive value of interferon- release assays for incident active tuberculosis: A systematic review and meta-analysis
Background: We aimed to assess whether interferon- release assays (IGRAs) can predict the development of active tuberculosis and whether the predictive ability of these tests is better than that of...
Antifungal interventions for the primary prevention of cryptococcal disease in adults with HIV
BACKGROUND: Cryptococcal disease is an opportunistic infection that causes significant morbidity and mortality in adults with HIV. Primary prophylaxis with antifungal interventions may decrease cryptococcal disease incidence and associated mortality....
Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States
A meta-analysis was performed to examine the effects of 14 behavioral and social interventions for heterosexual adults on their adoption of safer sex behaviors or incidence of sexually transmitted diseases...
Herpes simplex virus type 2 and HIV disease progression: A systematic review of observational studies
BACKGROUND: Herpes simplex virus type 2 (HSV-2) is a common co-infection among HIV-infected adults that is hypothesized to accelerate HIV disease progression. METHODS: We searched Medline, EMBASE, relevant conference proceedings...
