Category Archives: Co-infections
HIV infection and sexual risk behaviour among youth who have experienced orphanhood: Systematic review and meta-analysis
BACKGROUND: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and...
Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients
XST: This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical abstract contains a brief summary of the review methods, results...
Impact of HIV and sexual health education on the sexual behaviour of young people: A review update
To assess the effects of HIV/AIDS and sexual health education on young peoples sexual behaviour, a comprehensive literature review was commissioned by the Department of Policy, Strategy, and Research of...
Deworming helminth co-infected individuals for delaying HIV disease progression
BACKGROUND: The HIV-1 pandemic has disproportionately affected individuals in resource-constrained settings. These areas often also have high prevalence of other infectious diseases, such as helminth infections. It is important to...
Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: A meta-analysis
BACKGROUND: There are conflicting data in the medical literature regarding the degree of immune restoration (as measured by CD4 cell count) in patients who commence highly active antiretroviral therapy (HAART)...
Risk of window period hepatitis-C infection in high infectious risk donors: Systematic review and meta-analysis
The OPTN classifies high infectious risk donors (HRDs) based on criteria originally intended to identify people at risk for HIV infection. These donors are sometimes referred to as ‘CDC high...
Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: A meta-analysis
Objectives: To estimate stage-specific transition probabilities in individuals coinfected with HIV and hepatitis C virus (HCV), to examine the effect of covariates on these rates, and to investigate the effect...
Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients
Background Polymorphisms in the IL-28B region are a strong predictor of sustained virologic response (SVR) in individual studies of HCV genotype 1 patients receiving peginterferon (pegIFN) and ribavirin. Aim To...
A decline in HIV and syphilis epidemics in Chinese female sex workers (2000-2011): A systematic review and meta-analysis
BACKGROUND: Female sex workers (FSWs) play an important role in transmitting HIV and syphilis from high-risk groups to the general population. However, the trends in HIV and syphilis epidemics in...
