Category Archives: Co-infections
Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis
Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine...
The efficacy of behavioral interventions in reducing HIV risk behaviors and incident sexually transmitted diseases in heterosexual African Americans
Objective:: To conduct a meta-analytic review of HIV interventions for heterosexual African Americans to determine the overall efficacy in reducing HIV-risk sex behaviors and incident sexually transmitted diseases and identify...
HIV-1 and intestinal helminth review update: Updating a Cochrane Review and building the case for treatment and has the time come to test and treat?
Intestinal helminth infection activates and dysregulates the immune system and impacts the host’s capacity to respond to illness. Such neglected tropical infections exact the greatest burden on resource-limited settings and...
Intermittent preventive therapy for malaria during pregnancy using 2 vs 3 or more doses of sulfadoxine-pyrimethamine and risk of low birth weight in Africa: Systematic review and meta-analysis.
Background: Intermittent Preventive Therapy with sulfadoxine- pyrimethamine (IPTp-SP) for malaria in pregnancy is widely used in sub-Saharan Africa. Most countries use a 2-dose regimen given in the 2nd and 3rd...
Hepatitis C in patients with human immunodeficiency virus infection: Diagnosis, natural history, meta-analysis of sexual and vertical transmission, and therapeutic issues
Hepatitis C (HCV) infection occurs in as many as 33% of the patients with human immunodeficiency virus (HIV) infection. In view of their improved survival, liver disease will become more...
Suppression of HBV by tenofovir in HBV/HIV coinfected patients: A systematic review and meta-analysis.
BACKGROUND: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available...
Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis
The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...
Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts
There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...
Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis
BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...
Pulmonary tuberculosis in severely-malnourished or HIV-infected children with pneumonia: A review
Presentation of pulmonary tuberculosis (PTB) as acute pneumonia in severely-malnourished and HIV-positive children has received very little attention, although this is very important in the management of pneumonia in children...
Opiate substitution treatment and HIV transmission in people who inject drugs: Systematic review and meta-analysis
Objective To quantify the effect of opiate substitution treatment in relation to HIV transmission among people who inject drugs. Design Systematic review and meta-analysis of prospective published and unpublished observational...
