Category Archives: Co-infections
Interferon-γ release assays for active pulmonary tuberculosis diagnosis in adults in low-and middle-income countries: Systematic review and meta-analysis
Background. The diagnostic value of interferon- release assays (IGRAs) for active tuberculosis in low- and middle-income countries is unclear. Methods. We searched multiple databases for studies published through May 2010...
Interferon-gamma release assays for the diagnosis of tuberculosis and tuberculosis infection in HIV-infected adults: A systematic review and meta-analysis
BACKGROUND: Despite the widespread use of interferon-gamma release assays (IGRAs), their role in diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains unclear. We conducted a comprehensive systematic review...
Factors associated with patient and health care system delay in diagnosis and treatment for TB in sub-Saharan African countries with high burdens of TB and HIV
OBJECTIVE: To identify factors causing delayed diagnosis and treatment for tuberculosis in high tuberculosis (TB)/HIV burden African countries. METHODS: We searched Ovid Medline, CINAHL, PsychInfo, Scopus and Sabinet-South African journals...
Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: A systematic review and meta-analysis
Intensified case finding is the regular screening for evidence of tuberculosis in people infected with HIV, at high risk of HIV, or living in congregate settings. We systematically reviewed studies...
Estimating the resource needs of scaling-up HIV/AIDS and tuberculosis interventions in sub-Saharan Africa: A systematic review for national policy makers and planners
Considerable effort has been made to estimate the global resource requirements of scaling-up HIV/AIDS and tuberculosis (TB) interventions. There are currently several medium- and long-term global estimates available. Comprehensive country...
Population-based interventions for reducing sexually transmitted infections, including HIV infection
BACKGROUND: Sexually transmitted infections (STI) are common in developing countries. The World Health Organisation (WHO) estimates that in 1999, 340 million new cases of syphilis, gonorrhoea, chlamydial infection and trichomoniasis...
Does trimethoprim-sulfamethoxazole prophylaxis for HIV induce bacterial resistance to other antibiotic classes? Results of a systematic review
BACKGROUND: Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis has long been recommended for immunosuppressed HIV-infected adults and children born to HIV-infected women. Despite this, many resource-limited countries have not implemented this recommendation, partly because...
Water, sanitation, and hygiene interventions to improve health among people living with HIV/AIDS: A systematic review
DESIGN:: People living with HIV/AIDS (PLHIV) are at increased risk of diarrhoeal disease and enteric infection. This review assesses the effectiveness of water, sanitation, and hygiene (WASH) interventions to prevent...
Burden of HIV-related CMV retinitis in resource-limited settings: A systematic review
Background. Cytomegalovirus (CMV) is a late stage opportunistic infection in people living with HIV/AIDS. Lack of ophthalmological diagnostic skills or convenient CMV treatment and increasing access to antiretroviral therapy, have...
