Category Archives: Co-morbidities
Higher cardiovascular disease risks in people living with HIV: A systematic review and meta-analysis
Background The prognosis of AIDS after active antiretroviral therapy (ART) and the quality of life of people living with HIV (PLWH) are both affected by non-AIDS-related diseases such as cardiovascular...
Pulmonary hypertension survival and hospitalisations in people living with HIV: A systematic review and meta-analysis
INTRODUCTION: People living with HIV (PLHIV) have a higher risk of developing pulmonary hypertension (PH) with subsequent poorer prognosis. This review aimed to determine the (1) survival outcomes and (2)...
Biological depiction of lipodystrophy and its associated challenges among HIV AIDS patients: Literature review
Lipodystrophy syndrome is a medical condition characterized by the absence of adipose tissue without any underlying starvation or macromolecule breakdown. In HIV AIDS patients, the use of highly active antiretroviral...
The impact of social determinants of health on outcomes among individuals with HIV and heart failure: A literature review
This narrative review examines the complex interplay between social determinants of health (SDoH) and the outcomes for individuals living with human immunodeficiency virus (HIV) and heart failure (HF), two conditions...
Health-related quality of life measures provide information on the contributors, components, and consequences of frailty in HIV: A systematic mapping review
Purpose: Frailty in HIV is extensively explored in epidemiological and clinical studies; it is infrequently assessed as an outcome in routine care. The focus on health-related quality of life (HRQL) measures...
Effects of Tenofovir disoproxil fumarate on bone quality beyond bone density—A scoping review of the literature
Tenofovir disoproxil fumarate (TDF) is a widely used pharmacological agent for the treatment of human immunodeficiency virus infection. While prolonged exposure to TDF has been associated with a decrease in...
Acute kidney injury and its predictors among HIV-positive patients in Africa: Systematic review and meta-analysis
BACKGROUND: Acute kidney injury (AKI) is a rapid loss of the kidney’s excretory function, resulting in an accumulation of end products of nitrogen metabolism. The causes of AKI in HIV-positive...
High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: A systemic review and meta-analysis
The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The current systematic review...
Endothelial dysfunction, a predictor of cardiovascular disease in HIV patients on antiretroviral therapy: A systematic review and meta-analysis
Aim Although antiretroviral therapy (ART) is available, the rate of new HIV infections is alarming. With this trend, it is anticipated that the use of ART will continue to rise,...
Facility-based indicators to manage and scale up cervical cancer prevention and care services for women living with HIV in sub-Saharan Africa: A three-round online Delphi consensus method
BACKGROUND: Of women with cervical cancer (CC) and HIV, 85% live in sub-Saharan Africa, where 21% of all CC cases are attributable to HIV infection. We aimed to generate internationally...
Screening and prevention of HPV-related anogenital cancers in women living with HIV in Europe: Results from a systematic review
Background Women living with HIV (WLWH) are at increased risk of human papillomavirus (HPV)-related cancers. Throughout Europe, there is great heterogeneity among guidelines for screening programmes, access to HPV testing...
Regional variation in NAFLD prevalence and risk factors among people living with HIV in Europe: A meta-analysis
BACKGROUND AND AIM: Europe faces an elevated risk of nonalcoholic fatty liver disease (NAFLD) among people living with HIV (PLWH), contributing to the region’s highest global burden of NAFLD. However,...
