Category Archives: Age related disorders

The burden of sarcopenia in people living with HIV: A systematic review and meta-analysis across WHO regions

2026

BACKGROUND: Sarcopenia, characterized by progressive loss of skeletal muscle mass and function, represents an underrecognized comorbidity in people living with human immunodeficiency virus, and comprehensive prevalence data across WHO regions...

The prevalence and influencing factors of frailty among middle-aged and older adults with HIV/AIDS from a global perspective: A systematic review and meta-analysis

2026

Aim: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve frailty...

Polypharmacy in HIV: Rethinking what counts and why it matters

2025

Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age-related co-morbidities. However, how polypharmacy...

Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: A systematic review

2026

Background As people living with HIV (PWH) in Latin America and the Caribbean (LAC) have longer life expectancy due to improved access to antiretroviral therapy (ART), complications such as HIV-associated...

Challenges to physical activity participation among older people living with HIV: Scoping review

2025

Older people living with Human Immunodeficiency Virus (OPLWH) have lower physical activity levels than other population groups. Inadequate physical activity participation increases the risks of age-related non-communicable diseases (NCDs). Therefore,...

Sensory neuropathy and associated factors among patients living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Introduction Despite high prevalence of sensory neuropathy among individuals living with HIV, there is no comprehensive information regarding variables that determine sensory neuropathy onset among the patients who attended health...

Aging and HIV: Recent findings in contributing factors

2025

Background: Aging among people living with HIV (PLWH) presents multifaceted challenges influenced by antiretroviral therapy (ART), chronic inflammation, viral coinfections, stigma, multimorbidity, and immunosuppression. Methods: This review synthesizes recent research...

Experiences of older people living with human immunodeficiency virus comorbidity attending coordinated healthcare services

2025

BACKGROUND: Older people living with human immunodeficiency virus (OPLWHIV) on antiretroviral therapy are aging and face an increased risk of non-communicable diseases. The burden is costly and demands sustainable care...

Risk factors and mortality outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis

2024

This study was performed to reveal the risk factors associated with mortality in people living with HIV (PLHIV) who were diagnosed with COVID-19. Studies reporting deaths among PLHIV and infected...

The long-term health outcomes of people living with perinatal human immunodeficiency virus: A scoping review

2024

Since the first reported cases of perinatally acquired human immunodeficiency virus (HIV) in 1982, a generation born with HIV has reached adulthood. The authors conducted a scoping review of PubMed...

A scoping review of observational research on cannabis use for symptom management in HIV and cancer: Implications for cannabis nursing

2024

Background: People with HIV have a higher risk of developing non-AIDS-defining cancers in older age, leading to a significant population living with two conditions, HIV and cancer. There is an increasing...

“It’s like it’s the old boys club”—The age-related experiences of diverse older women living with HIV: A scoping review and consultative exercise

2024

Objectives HIV is often under-recognized in older individuals, particularly women, despite a significant number of new cases being diagnosed in those aged >50 years. This review aimed to understand the age-related...

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