Category Archives: Cancer
Influence of statin therapy on the incidence of cardiovascular events, cancer, and all-cause mortality in people living with HIV: A meta-analysis
Background: Possible influences of statin therapy on the risk of cardiovascular events, cancer, and all-cause mortality in people living with HIV (PLWH) remain unclear. We performed a meta-analysis to systematically evaluate...
Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: An immunologic and pathobiologic review
BACKGROUND: Anal squamous cell carcinoma (SCC) is a rare gastrointestinal malignancy with rising incidence, both in the United States and internationally. The primary risk factor for anal SCC is human...
Prevalence of high-risk HPV genotypes in sub-Saharan Africa according to HIV status: A 20-year systematic review
OBJECTIVES: This review assessed the rate of high-risk human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency...
Differences in outcomes of chemoradiation in women with invasive cervical cancer by human immunodeficiency virus status: A systematic review
PURPOSE: Cervical cancer is one of the leading causes of cancer death among women worldwide, and women living with human immunodeficiency virus (HIV) carry the highest burden of disease. Chemoradiation...
A review of chronic comorbidities in adults living with HIV: State of the science
People living with HIV are living longer, high-quality lives; however, as they age, this population is at increased risk for developing chronic comorbidities, including cardiovascular disease, certain types of cancer...
The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer
Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...
High-risk human papillomavirus infection among women living with HIV in Latin America and the Caribbean: A systematic review and meta-analysis
We carried out a systematic review to summarize available data regarding prevalence of high-risk human papillomavirus (HR-HPV) among women living with HIV (WLHIV) in Latin America and the Caribbean (LAC)....
Treatment of pre- and confirmed cervical cancer in HIV-seropositive women from developing countries: A systematic review
BACKGROUND: Cervical cancer has become a major public health challenge in developing countries with a reported age-standardised incidence rate of about 17.9/100,000/year and lifetime risks approaching 1 in 20 in...
Prevalence of high-risk HPV genotypes in sub-Saharan Africa based on human immunodeficiency virus status: A 20-year systematic review
This review assessed the rate of high-risk Human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency virus...
Impact of antiretroviral therapy on cancer treatment outcomes among people living with HIV in low- and middle-income countries: A systematic review
PURPOSE OF REVIEW: The relationship between antiretroviral therapy (ART) and cancer treatment outcomes among people living with HIV (PLWH) in low- and middle-income countries (LMICs) is complex and poorly understood...
