Category Archives: Cardiovascular
Effectiveness of statins in people living with HIV: A systematic review and meta-analysis of randomized controlled trials
Introduction: People living with HIV (PLWH) receiving statin therapy have shown improved lipid profiles. However, they are not free from side effects, thereby requiring strict monitoring of the therapy. The meta-analysis...
Higher cardiovascular disease risks in people living with HIV: A systematic review and meta-analysis
Background The prognosis of AIDS after active antiretroviral therapy (ART) and the quality of life of people living with HIV (PLWH) are both affected by non-AIDS-related diseases such as cardiovascular...
The impact of social determinants of health on outcomes among individuals with HIV and heart failure: A literature review
This narrative review examines the complex interplay between social determinants of health (SDoH) and the outcomes for individuals living with human immunodeficiency virus (HIV) and heart failure (HF), two conditions...
Pulmonary hypertension survival and hospitalisations in people living with HIV: A systematic review and meta-analysis
INTRODUCTION: People living with HIV (PLHIV) have a higher risk of developing pulmonary hypertension (PH) with subsequent poorer prognosis. This review aimed to determine the (1) survival outcomes and (2)...
High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: A systemic review and meta-analysis
The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The current systematic review...
Endothelial dysfunction, a predictor of cardiovascular disease in HIV patients on antiretroviral therapy: A systematic review and meta-analysis
Aim Although antiretroviral therapy (ART) is available, the rate of new HIV infections is alarming. With this trend, it is anticipated that the use of ART will continue to rise,...
Cardio-metabolic health of offspring exposed in utero to human immuno-deficiency virus and anti-retroviral treatment: A systematic review
BACKGROUND: Antiretroviral treatment (ART) use during pregnancy continues to rise as it is known to decrease the likelihood of HIV transmission from mother to child. However, it is still unknown...
Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis
The association between human immunodeficiency virus (HIV) status and readmissions and death outcomes in patients with established heart failure (HF) remains unclear. We conducted a systematic search of PubMed, EMBASE,...
Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis
Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...
Cardiovascular challenges in the era of antiretroviral therapy for AIDS/ HIV: A comprehensive review of research advancements, pathophysiological insights, and future directions
Cardiovascular disease, particularly coronary heart disease, is becoming more common among those living with HIV. Individuals with HIV face an increased susceptibility to myocardial infarction, also known as a heart...
The impact of contemporary antiretroviral drugs on atherosclerosis and its complications in people living with HIV: A systematic review
With thWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV...
