Category Archives: Other
Impact of antiretroviral therapy on serum lipoprotein levels and dyslipidemias: A systematic review and meta-analysis
BACKGROUND: Antiretroviral drugs increase biosynthesis and reduce hepatic clearance of serum cholesterol. It is thus important to evaluate the impact of antiretroviral treatment on serum lipoprotein levels and the risk...
Comparative effectiveness of tenofovir in treatment-naive HIV-infected patients: Systematic review and meta-analysis
INTRODUCTION: Benefits and harms of tenofovir disoproxil fumarate (TDF) in HIV-infected, antiretroviral treatment (ART)-naive patients of any age have not been systematically reviewed since recent milestone trials were published. METHODS:...
Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function
OBJECTIVE: To evaluate the apparent association of human immunodeficiency virus (HIV) infection, antiretroviral therapy (ART), and protease inhibitor (PI) exposure with the functional and structural markers of vasculature. METHODS: A...
Long-term immune responses to vaccination in HIV-infected patients: A systematic review and meta-analysis
Vaccine-induced antibodies may wane more quickly in persons living with human immunodeficiency virus (HIV) than in healthy individuals. We reviewed the literature on vaccines routinely recommended in HIV-infected patients to...
HIV, antiretroviral therapy, and hypertensive disorders in pregnancy: A systematic review and meta-analysis
BACKGROUND: There are data to suggest that infection with HIV or use of highly active antiretroviral therapy increases the risk of hypertensive disorders in pregnancy. This systematic review and meta-analysis...
Is there enough evidence to use bisphosphonates in HIV-infected patients? A systematic review and meta-analysis
An increased prevalence of osteopenia and osteoporosis has been observed in HIV-infected cohorts. We investigated the effect of bisphosphonates on bone mineral density in adults with HIV infection. Outcomes of...
Hepatitis C virus increases the risk of kidney disease among HIV-positive patients: Systematic review and meta-analysis
BACKGROUND: Kidney disease has become an important co-morbidity among human immunodeficiency virus-infected patients as they live longer in the era of highly effective antiretroviral therapy. It remains unclear how co-infection...
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
Growth hormone axis treatments for HIV-associated lipodystrophy: A systematic review of placebo-controlled trials
BACKGROUND: HIV-associated lipodystrophy is a disorder of fat metabolism that occurs in patients with HIV infection. It can cause metabolic derangements and negative self-perceptions of body image, and result in...
Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review
AIM: To investigate the diagnosis, pathogenesis, natural history, and management of nodular regenerative hyperplasia (NRH) in patients with human immunodeficiency virus (HIV). METHODS: We performed a systematic review of the...
