Category Archives: Other
A scoping review of lung function in children and adolescents living with HIV in the era of antiretroviral treatment
Background: Human immunodeficiency virus (HIV) in children and adolescents remains an important health challenge in many countries and is commonly associated with lung disease. The introduction of antiretroviral therapy (ART) has...
Prevalence and influences of diabetes and prediabetes among adults living with HIV in Africa: A systematic review and meta-analysis
INTRODUCTION: In people living with human immunodeficiency virus (PLHIV), traditional cardiovascular risk factors, exposure to HIV per se and antiretroviral therapy (ART) are assumed to contribute to cardiometabolic diseases. Nevertheless,...
New onset type 2 diabetes mellitus risks with integrase strand transfer inhibitors-based regimens: A systematic review and meta-analysis
Objectives: The development of diabetes mellitus (DM) in patients taking integrase strand transfer inhibitors (INSTIs) has raised concerns. It’s critical because, in most guidelines, INSTIs are the preferred third agent at...
Uncovering the NAFLD burden in people living with HIV from high- and middle-income nations: A meta-analysis with a data gap from Subsaharan Africa
INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) has become a significant concern among people living with HIV (PLHIV), albeit its burden remains unclear. The primary objective of this systematic review (SR)...
The effect of antiretroviral therapy on the periodontal conditions of patients with HIV infection: A systematic review and meta-analysis
Aim: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART) and...
Prevalence of hepatotoxicity among HIV-infected patients in Ethiopia: A systematic review and meta-analysis
Background: Globally, the human immunodeficiency virus has been recognized as a major public health concern. The direct toxicity of antiretroviral medicines or their active metabolites causes liver cell destruction by different...
Global prevalence and associated clinical markers of thrombocytopenia in people living with HIV: Evidence from meta-analysis
Thrombocytopenia is one of the complications in human immunodeficiency virus (HIV) patients. To improve the health outcomes of patients living with HIV, it is important to understand the prevalence and...
A systematic review of four decades of prevalence of oral soft tissue infections and conditions among adult HIV patients in India
Oral lesions are a cue for decreased immunity among Human Immunodeficiency Virus (HIV) positive patients. There is no cumulative data available related to the prevalence of oral soft tissue lesions...
Apolipoprotein L1 gene variants and kidney disease in patients with HIV: A systematic review and meta-analysis
Background: The risk of various types of kidney disease is significantly increased in the presence of APOL1 high-risk genotype (carriage of two risk alleles), particularly HIV-associated nephropathy (HIVAN). However, there are...
The association between physical frailty and injurious falls and all-cause mortality as negative health outcomes in people living with HIV: A systematic review and meta-analysis
Objectives: Physical frailty is one of the major concerns among older people living with HIV (PLWH). This meta-analysis aimed to explore the association between physical frailty and negative health outcomes among...
Prevalence and characteristics of nonalcoholic fatty liver disease and fibrosis in people living with HIV monoinfection: A systematic review and meta-analysis
Background and Aims Liver disease remains a leading cause of morbidity and mortality among people living with HIV (PLWH). Emerging data have shown that PLWH are at high risk for...
Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review
OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries...
