Category Archives: Co-morbidities
Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability
Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...
Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis
Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and...
Oral health education interventions for people living with HIV: A scoping review of delivery approaches and reported outcomes
Background People living with HIV (PLWH) experience a high burden of oral diseases that can impair daily function and affect adherence to HIV care. Oral health education has the potential...
Colorectal cancer screening uptake and lesion detection in people living with HIV: A systematic review and meta-analysis
Introduction: As people living with HIV age, the absolute colorectal cancer (CRC) burden rises, yet the extent of routine CRC screening delivery and clinical yield is unclear. We synthesized evidence on...
Prevalence of cardiometabolic diseases among ART-naïve people with HIV: A global systematic review and meta-analysis
Introduction The burden of cardiometabolic diseases (CMDs) is rising in people with HIV (PWH). While extensive data exist on CMD prevalence in PWH receiving antiretroviral therapy (ART), comprehensive data on...
Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review
Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Cardiovascular diseases among people living with HIV/AIDS in Ethiopia: A scoping review
Background Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) remains a significant burden in Ethiopia. People living with HIV/AIDS (PLWHA) are at increased risk of cardiovascular diseases due to both...
Prevalence of chronic kidney disease and associated factors among adult HIV patients in Africa: A systematic review and meta-analysis
Introduction: A number of individual studies in Africa reporting the prevalence of chronic kidney disease (CKD) among people living with HIV are becoming more common. This analysis aims to combine...
The emerging role of Interleukin-32 in HIV-associated cardiovascular comorbidities: A mini review
With the widespread use of antiretroviral therapy (ART), the life expectancy of people living with HIV (PLWH) has significantly improved. However, the incidence of cardiovascular disease (CVD) in this population...
Lived experiences of cancer care for people living with HIV who are treated for anal cancer: A scoping review
OBJECTIVE: This scoping review aims to identify existing evidence on the lived experiences of people living with HIV and treated for anal cancer, and to identify what aspects of health...
Inflammatory biomarkers predicting major adverse cardiovascular events in people living with HIV: A systematic review and meta-analysis
Introduction Chronic inflammation is a unique contributor to cardiovascular disease (CVD) risk among people living with HIV, yet there is a lack of consensus on the predictive utility of inflammatory...
