Category Archives: Co-morbidities
Prevalence of left ventricular systolic dysfunction in HIV-infected children from sub-Saharan Africa: A systematic review and meta-analysis
Background Left ventricular systolic dysfunction (LVSD) is an emerging non-communicable complication among children living with Human Immunodeficiency Virus (HIV), particularly in Sub-Saharan Africa, where paediatric HIV burden remains high. However,...
Prevalence of hypertension, diabetes, obesity, and high cholesterol among older people living with HIV: A systematic review and meta-analysis
INTRODUCTION: Metabolic comorbidities are significant health challenges for older people living with HIV (PLHIV). This systematic review and meta-analysis aimed to synthesize existing evidence and provide the pooled prevalence of...
Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care
People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...
Colorectal cancer screening uptake and lesion detection in people living with HIV: A systematic review and meta-analysis
Introduction: As people living with HIV age, the absolute colorectal cancer (CRC) burden rises, yet the extent of routine CRC screening delivery and clinical yield is unclear. We synthesized evidence on...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Prevalence of cardiometabolic diseases among ART-naïve people with HIV: A global systematic review and meta-analysis
Introduction The burden of cardiometabolic diseases (CMDs) is rising in people with HIV (PWH). While extensive data exist on CMD prevalence in PWH receiving antiretroviral therapy (ART), comprehensive data on...
Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review
Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...
Cardiovascular diseases among people living with HIV/AIDS in Ethiopia: A scoping review
Background Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) remains a significant burden in Ethiopia. People living with HIV/AIDS (PLWHA) are at increased risk of cardiovascular diseases due to both...
The emerging role of Interleukin-32 in HIV-associated cardiovascular comorbidities: A mini review
With the widespread use of antiretroviral therapy (ART), the life expectancy of people living with HIV (PLWH) has significantly improved. However, the incidence of cardiovascular disease (CVD) in this population...
Prevalence of chronic kidney disease and associated factors among adult HIV patients in Africa: A systematic review and meta-analysis
Introduction: A number of individual studies in Africa reporting the prevalence of chronic kidney disease (CKD) among people living with HIV are becoming more common. This analysis aims to combine...
Lived experiences of cancer care for people living with HIV who are treated for anal cancer: A scoping review
OBJECTIVE: This scoping review aims to identify existing evidence on the lived experiences of people living with HIV and treated for anal cancer, and to identify what aspects of health...
Inflammatory biomarkers predicting major adverse cardiovascular events in people living with HIV: A systematic review and meta-analysis
Introduction Chronic inflammation is a unique contributor to cardiovascular disease (CVD) risk among people living with HIV, yet there is a lack of consensus on the predictive utility of inflammatory...
