Category Archives: Co-morbidities
A review of chronic comorbidities in adults living with HIV: State of the science
People living with HIV are living longer, high-quality lives; however, as they age, this population is at increased risk for developing chronic comorbidities, including cardiovascular disease, certain types of cancer...
The intersection of cognitive ability and HIV: A review of the state of the nursing science
Neurocognitive problems have been endemic to the HIV epidemic since its beginning. Four decades later, these problems persist, but currently, they are attributed to HIV-induced inflammation, the long-term effects of...
Mechanisms and primary prevention of atherosclerotic cardiovascular disease among people living with HIV
PURPOSE OF REVIEW: To highlight mechanisms of elevated risk of atherosclerotic cardiovascular disease (ASCVD) among people living with HIV (PLWH), discuss therapeutic strategies, and opportunities for primary prevention. RECENT FINDINGS:...
The prevalence of hypogonadism and the effectiveness of androgen administration on body composition in HIV-infected men: A meta-analysis
BACKGROUND: Hypogonadism is a common comorbidity in human immunodeficiency virus (HIV)-infected men, although the real prevalence is difficult to be estimated. Moreover, in HIV settings, the efficacy of exogenous testosterone...
Comparative efficacy of antifungal agents used in the treatment of oropharyngeal candidiasis among HIV-infected adults: A systematic review and network meta-analysis
The objective of this study was to assess the comparative efficacy and safety of different antifungal agents used for the treatment of oropharyngeal candidiasis (OPC) in adult patients with HIV....
Nutrition in HIV-infected infants and children: Current knowledge, existing challenges, and new dietary management opportunities
HIV infection and undernutrition remain significant public health concerns for infants and children. In infants and children under these conditions, undernutrition is one of the leading causes of death. Proper...
A systematic review and meta-analysis of studies evaluating the effect of medication treatment for opioid use disorder on infectious disease outcomes
The opioid epidemic has fueled infectious disease epidemics. We determined the impact of medications for opioid use disorder (MOUD) on treatment outcomes of opioid use disorder (OUD)-associated infectious diseases: antiretroviral...
The manifesto of pharmacoenosis: Merging HIV pharmacology into pathocoenosis and syndemics in developing countries
Pathocoenosis and syndemics theories have emerged in the last decades meeting the frequent need of better understanding interconnections and reciprocal influences that coexistent communicable and non-communicable diseases play in a...
Increased risk of vitamin D deficiency among HIV-infected individuals: A systematic review and meta-analysis
Background: Human immunodeficiency virus (HIV) infection is a heavy burden worldwide. Observational studies have reported a high prevalence of vitamin D deficiency (VDD) among people living with HIV (PLWH). However,...
The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer
Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...
