Category Archives: Co-morbidities

Implementation of Cholesterol-Lowering Therapy to Reduce Cardiovascular Risk in Persons Living with HIV

2020

The widespread availability of highly effective antiretroviral therapies has reduced mortality from opportunistic infections in persons living with HIV (PLHIV), resulting in an increase in atherosclerotic cardiovascular disease (ASCVD) and...

Kidney Transplantation in HIV Positive Patients: Current Practice and Management Strategies

2020

BACKGROUND: HIV positive patients had been successfully transplanted for the last 15 years and the donor pool had successfully been expanded to also include HIV positive donors. METHODS: We aimed...

Impact of human immunodeficiency virus (HIV) infection in patients undergoing cardiac surgery: A systematic review

2020

The clinical status and prognosis of patients with human immunodeficiency virus (HIV) infection has dramatically changed in the recent years. Cardiovascular diseases can be related to combined antiretroviral therapy and...

Haemophagocytic lymphohistiocytosis in human immunodeficiency virus: A systematic review of literature

2020

Diagnosis and management of hemophagocytic lymphohistiocytosis (HLH) in patients with human immunodeficiency virus (HIV) infection are scarcely described in the published literature. The aim of this systematic review was to...

Barriers to cervical cancer screening among women living with HIV in low- and middle-income countries: A systematic review

2020

Women living with HIV in low-and-middle-income countries (LMICs) are at high risk of developing cervical cancer due to their immunocompromised status. Screening is an imperative prevention measure for early detection...

Patients’ self-reported factors influencing cervical cancer screening uptake among HIV-positive women in low- and middle-income countries: An integrative review

2020

Cervical cancer is among the most common causes of cancer-related deaths in low- and middle-income countries (LMICs). Despite the strong evidence regarding cervical cancer screening cost-effectiveness, its utilization remains low...

Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review

2020

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...

Aging with HIV

2019

PURPOSE OF REVIEW: This review points out unmet medical needs and open research questions of older adults living with HIV. Starting from the definition of aging in HIV, it explores...

QT prolongation in HIV-positive patients: Review article

2019

INTRODUCTION: Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. METHODS: Pubmed and Google Scholar...

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Global burden of hypertension among people living with HIV in the era of increased life expectancy: A systematic review and meta-analysis

2020

BACKGROUND: Although HIV infection and antiretroviral therapy (ART) increase the risk for hypertension in people living with HIV (PLHIV), the global and regional burden of hypertension in PLHIV is not...

A comparative analysis of blood pressure in HIV-infected patients versus uninfected controls residing in Sub-Saharan Africa: A narrative review

2020

Elevated blood pressure (BP) is an important risk factor for cardiovascular disease and mortality in Sub-Saharan Africa (SSA). We reviewed the literature comparing BP in treated HIV-infected populations against untreated...

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