Category Archives: Co-morbidities

The accuracy of anal swab-based tests to detect high-grade anal intraepithelial neoplasia in HIV-infected patients: A systematic review and meta-analysis

2019

Background: The incidence of high-risk human papillomavirus (HR-HPV)-induced anal cancer is increasingly problematic among HIV-positive patients. Anal cancer is preceded by precursor lesions, anal intraepithelial neoplasia (AIN). AIN detection requires...

Precancerous cervical lesion among HIV-positive women in sub-Saharan Africa: A systematic review and meta-analysis

2019

In sub-Saharan Africa, cervical cancer is an intersecting epidemic with HIV and it is the second most common cause of cancer-related deaths in women. Therefore, this study was aimed to...

Patho-immune mechanisms of hypertension in HIV: A systematic and thematic review

2019

PURPOSE OF REVIEW: To systematically review recent findings on the role of immune cell activation in the pathogenesis of hypertension in people living with HIV (PLWH) and compare studies from...

Pulmonary hypertension in the global population of adolescents and adults living with HIV: A systematic review and meta-analysis

2019

A systematic review and meta-analysis was conducted to estimate the prevalence of PH in adolescents and adults living with HIV at the global level. PubMed, EMBASE, Web of Science, and...

Gestational diabetes mellitus in HIV-infected pregnant women: A systematic review and meta-analysis

2019

BACKGROUND: Impaired glucose metabolism during pregnancy can result in a significant adverse pregnancy-outcomes. Previous studies have reported the contribution of ART to the impaired glucose tolerance and gestational diabetes mellitus...

Tenofovir-associated kidney disease in Africans: A systematic review

2019

BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...

Treatment outcomes of patients with localized anal squamous cell carcinoma according to HIV infection: Systematic review and meta-analysis

2019

Background: Definitive chemoradiation (CRT) is the standard treatment for localized squamous cell carcinoma of the anus (SCCA). Because most phase III trials in SCCA have excluded patients with HIV, the...

Gynecologic cancer in HIV-positive women: A systematic review and meta-analysis

2019

BACKGROUND: While there is a significant body of literature on cervical cancer in HIV-positive women, little is known about other gynecologic cancers in this population. OBJECTIVE: The objective of this...

Managing pharmacotherapy in people living with HIV and concomitant malignancy

2019

OBJECTIVE: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations...

Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus

2019

BACKGROUND: Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its...

Factors associated with excess myocardial infarction risk in HIV-infected adults: A systematic review and meta-analysis

2019

OBJECTIVES: To estimate the pooled relative risk of incident acute myocardial infraction (AMI) among HIV-infected adults compared to HIV-uninfected controls and explore the contribution of traditional and HIV-related risk factors....

Effects of aerobic and resistance exercise on cardiovascular parameters for people living with HIV: A meta-analysis

2019

People living with HIV (PLWH) have limited exercise capacity because of anemia, neuromuscular disorders, and pulmonary limitations. We used a meta-analysis to examine the effect of aerobic and resistance exercise...

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