Category Archives: Co-morbidities
Difference in toxicity between HIV-positive and HIV-negative patients with squamous-cell cancer of the anal canal treated with concomitant radio-chemotherapy
Background: The incidence of squamous cell carcinoma of the anal canal has been increasing over the last 30 years. HIV has been found to be a risk factor for the...
Burden of anemia and its association with HAART in HIV infected children in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Anemia is a common problem in HIV (human immunodeficiency virus) infected patients, and is associated with decreased functional capacity and quality of life. Ethiopia is one of the countries...
Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies
BACKGROUND: People with HIV (PWHIV) have improved survival because of the advent of antiretroviral therapy. Consequently, PWHIV experience higher rates of non-acquired immunodeficiency syndrome-defining malignancies (NADMs). Previous studies have demonstrated...
Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors
BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...
Risk of myocardial infarction among people living with HIV: An updated systematic review and meta-analysis
OBJECTIVE: Cardiovascular disease (CVD) is one of the leading non-AIDS-defining causes of death among HIV-positive (HIV+) individuals. However, the evidence surrounding specific components of CVD risk remains inconclusive. We conducted...
Human immunodeficiency virus and risk of pre-eclampsia and eclampsia in pregnant women: A meta-analysis on cohort studies
Maternal HIV infection is related to several perinatal adverse outcomes. This study is aimed at establishing whether maternal HIV infection is associated with the development of pre-eclampsia (PE) and eclampsia....
The effect of HIV infection, antiretroviral therapy on carotid intima-media thickness: A systematic review and meta-analysis
AIMS: We performed a systematic review and meta-analysis on the effect of HIV infection and antiretroviral therapy (ART) on carotid intima-media thickness (cIMT) to elucidate the role of HIV infection...
Combined antiretroviral therapy for HIV and the risk of hypertensive disorders of pregnancy: A systematic review
OBJECTIVE: To assess if there is a relationship between use of combined antiretroviral therapy among pregnant women living with HIV and hypertensive disorders of pregnancy (HDP). DESIGN: Due to the...