Category Archives: Co-morbidities
The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: Scoping review
BACKGROUND: People living with HIV (PLHIV) are at a high risk of developing HPV-related cancers. HPV-related malignancies occur frequently and/or are high among PLHIV, with cervical cancer as a designated...
The safety and efficacy of immune checkpoint inhibitors in patients with advanced cancers and pre-existing chronic viral infections (Hepatitis B/C, HIV): A review of the available evidence
The treatment paradigm of several cancers has dramatically changed in recent years with the introduction of immunotherapy. Most oncology trials involving immune checkpoint inhibitors (ICIPs) have routinely excluded patients with...
Difference in toxicity between HIV-positive and HIV-negative patients with squamous-cell cancer of the anal canal treated with concomitant radio-chemotherapy
Background: The incidence of squamous cell carcinoma of the anal canal has been increasing over the last 30 years. HIV has been found to be a risk factor for the...
Burden of anemia and its association with HAART in HIV infected children in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Anemia is a common problem in HIV (human immunodeficiency virus) infected patients, and is associated with decreased functional capacity and quality of life. Ethiopia is one of the countries...
Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies
BACKGROUND: People with HIV (PWHIV) have improved survival because of the advent of antiretroviral therapy. Consequently, PWHIV experience higher rates of non-acquired immunodeficiency syndrome-defining malignancies (NADMs). Previous studies have demonstrated...
Heart failure among people with HIV: Evolving risks, mechanisms, and preventive considerations
PURPOSE: People with HIV (PHIV) with access to modern antiretroviral therapy (ART) face a two-fold increased risk of heart failure as compared with non-HIV-infected individuals. The purpose of this review...
Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors
BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...
Risk of myocardial infarction among people living with HIV: An updated systematic review and meta-analysis
OBJECTIVE: Cardiovascular disease (CVD) is one of the leading non-AIDS-defining causes of death among HIV-positive (HIV+) individuals. However, the evidence surrounding specific components of CVD risk remains inconclusive. We conducted...
