Category Archives: Co-morbidities
Which HIV patients should be screened for osteoporosis: An international perspective
PURPOSE OF REVIEW: This review provides international insights into the real-world clinical approach to screening for bone mineral density (BMD) and osteoporosis in people living with HIV (PLWH) using opinions...
Association between immune markers and surrogate markers of cardiovascular disease in HIV positive patients: A systematic review
BACKGROUND: HIV infection is associated with an increased risk of cardiovascular disease (CVD). Chronic low-grade immune activation is likely one of the driving mechanisms. This systematic review provides an overview...
Review of functional MRI in HIV: Effects of aging and medication
HIV-associated neurocognitive disorder (HAND) is a frequently occurring comorbidity of HIV infection. Evidence suggests this condition starts subclinical before a progression to a symptomatic stage. Blood oxygenated level dependent (BOLD)...
The association between alcohol use and cardiovascular disease among people living with HIV: A systematic review
BACKGROUND: People living with HIV-infection (PLWH) have higher prevalence and earlier onset of cardiovascular disease (CVD), compared to uninfected populations. It is unclear how alcohol consumption is related to CVD...
Atazanavir and cardiovascular risk among human immunodeficiency virus-infected patients: A systematic review
INTRODUCTION: Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular disease (CVD). While viral suppression with antiretroviral therapy decreases CVD risk overall, several studies have suggested...
Prevalence and incidence of pulmonary hypertension among HIV-infected people in Africa: A systematic review and meta-analysis
OBJECTIVE: Patients infected with HIV have a direly increased risk of developing pulmonary hypertension (PH), and of dying from the condition. While Africa carries the greatest burden of HIV infection...
Systematic review of prevalence and predictors of frailty in individuals with human immunodeficiency virus
OBJECTIVES: To describe the prevalence and predictors of frailty in individuals with the human immunodeficiency virus (HIV) using systematic review methodology. DESIGN: Review. SETTING: Community. PARTICIPANTS: Older adults with HIV....
The burden of mucormycosis in HIV-infected patients: A systematic review
OBJECTIVES: Mucormycosis is an invasive fungal infection afflicting immunocompromised patients, causing a significant degree of morbidity and mortality. The purpose of the study was to provide a comprehensive analysis describing...
A systematic review and meta-analysis of the relative efficacy and safety of treatment regimens for HIV-associated cerebral toxoplasmosis: Is trimethoprim-sulfamethoxazole a real option?
OBJECTIVES: The objective of this study was to perform a systematic review and meta-analysis of the literature to evaluate the efficacy and safety of therapies for cerebral toxoplasmosis in HIV-infected...