Category Archives: Co-morbidities
HIV-associated cardiovascular disease: Importance of platelet activation and cardiac fibrosis in the setting of specific antiretroviral therapies
HIV infection is a risk factor for cardiovascular disease (CVD). This risk is accentuated by certain combination antiretroviral therapies (cARTs), independent of their effects on lipid metabolism and insulin sensitivity....
Global burden of atherosclerotic cardiovascular disease in people living with the human immunodeficiency virus: A systematic review and meta-analysis
Background -With advances in anti-retroviral therapy, most deaths in people with human immune-deficiency virus (HIV) are now due to non-communicable illnesses especially cardiovascular disease. We determine the association between HIV...
The effect of bariatric surgery on patients with HIV infection: A literature review
Obesity among human immunodeficiency virus (HIV)-infected individuals is on the rise. Bariatric procedures such as Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) alter the GI tract. Whether this alteration...
A scoping review of the role of HIV-related stigma and discrimination in noncommunicable disease care
BACKGROUND: People living with HIV are increasingly burdened by noncommunicable diseases (NCDs) as a result of the NCD susceptibility that accompanies increased life expectancy and the rising global prevalence of...
Predictors of human immunodeficiency virus (HIV) infection in primary care among adults living in developed countries: A systematic review
BACKGROUND: Early diagnosis of human immunodeficiency virus (HIV) is important because antiretroviral therapies are more effective if infected individuals are diagnosed early. Diagnosis of HIV relies on laboratory testing and...
A review of long-term toxicity of antiretroviral treatment regimens and implications for an aging population
Human immunodeficiency virus (HIV) is a chronic infectious disease currently requiring lifelong antiretroviral therapy (ART). People living with HIV (PLWH) face an increased risk of comorbidities associated with aging, chronic...
Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: A systematic review and meta-analysis
OBJECTIVE: To appropriately identify and treat noncommunicable diseases (NCDs) among persons living with HIV (PLHIV) in low-and-middle-income countries (LMICs), it is imperative to understand the burden of NCDs among PLHIV...
Strategies for improving the lives of US women aged 40 and above living with HIV/AIDS: An evidence map
BACKGROUND: While in its early years the HIV epidemic affected primarily the male and the young, nowadays, the population living with HIV/AIDS is approximately 24% women, and its age composition...
Chronic kidney disease in the global adult HIV-infected population: A systematic review and meta-analysis
INTRODUCTION: The widespread use of antiretroviral therapies (ART) has increased life expectancy in HIV patients, predisposing them to chronic non-communicable diseases including Chronic Kidney Disease (CKD). We performed a systematic...
The association between HIV and atherosclerotic cardiovascular disease in sub-Saharan Africa: A systematic review
BACKGROUND: Sub-Saharan Africa (SSA) has confronted decades of the HIV epidemic with substantial improvements in access to life-saving antiretroviral therapy (ART). Now, with improved survival, people living with HIV (PLWH)...
Approach to acute kidney injury in HIV-infected patients in South Africa
Background: HIV-infected patients have an increased risk of renal disease. Current first-line antiretroviral therapy contains tenofovir disoproxil fumarate (TDF), which has nephrotoxic potential, characterised by proximal tubular cell injury. This...
