Category Archives: Co-morbidities

Reduced bone mineral density in human immunodeficiency virus-infected individuals: A meta-analysis of its prevalence and risk factors

2017

A meta-analysis was conducted to evaluate the prevalence of osteopenia/osteoporosis in human immunodeficiency virus (HIV)-infected individuals. The prevalence of osteopenia/osteoporosis in HIV-infected and antiretroviral therapy (ART)-treated individuals was significantly higher...

HIV-positive women have higher risk of HPV infection, precancerous lesions, and cervical cancer: A systematic review and meta-analysis

2018

OBJECTIVES: HIV-positive women have higher human papillomavirus (HPV) prevalence and cervical cancer (CC) incidence than HIV-negative women, partly due to HIV’s modifying effect on HPV pathogenesis. We synthesized the literature...

The world-wide incidence of Kaposi’s sarcoma in the HIV/AIDS era

2018

OBJECTIVES: Kaposi’s sarcoma (KS) is a multicentric angioproliferative cancer of endothelial origin typically occurring in the context of immunosuppression or immunodeficiency. Consequently, KS is one of the most common cancers...

Public health approach to prevent cervical cancer in HIV-infected women in Kenya: Issues to consider in the design of prevention programs

2017

Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds...

Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: A systematic review and meta-analysis

2018

BACKGROUND: Data on carcinogenicity of human papillomavirus (HPV) types in the anus are needed to inform anal cancer prevention through vaccination and screening. This is particularly the case for people...

Association of antiretroviral therapy with high-risk human papillomavirus, cervical intraepithelial neoplasia, and invasive cervical cancer in women living with HIV: A systematic review and meta-analysis

2018

Background The interactions between antiretroviral therapy (ART) and high-risk human papillomavirus (HPV) and cervical lesions in women living with HIV are poorly understood. We reviewed the association of ART with...

Association between the use of protease inhibitors in highly active antiretroviral therapy and incidence of diabetes mellitus and/or metabolic syndrome in HIV-infected patients: A systematic review and meta-analysis

2017

This systematic review and meta-analysis tries to determine whether there is an association between the use of protease inhibitors (PIs) and the incidence of diabetes mellitus (DM) and/or metabolic syndrome...

Effectiveness of n-3 fatty acids in the treatment of hypertriglyceridemia in HIV/AIDS patients: A meta-analysis

2017

Hypertriglyceridemia is common in antiretroviral therapy-treated patients and Omega 3 fatty acids are being used as a intervention in reducing serum triglycerides (TG) in these patients. The objective of this...

Exploring the views and experiences of HIV positive patients treated for cancer: A systematic review of the literature

2017

A systematic review of the literature was conducted to find out what is known about patients’ experiences of a dual diagnosis of HIV and cancer. We systematically searched the following...

Breast cancer and HIV: A South African perspective and a critical review of the literature

2017

BACKGROUND: The diagnosis of breast cancer and concurrent HIV in South Africa is common. The limited current evidence on this subject suggests that the patients thus afflicted appear to be...

Cervical cancer prevention and treatment research in Africa: A systematic review from a public health perspective

2016

BACKGROUND: Women living in Africa experience the highest burden of cervical cancer. Research and investment to improve vaccination, screening, and treatment efforts are critically needed. We systematically reviewed and characterized...

Renal manifestations of HIV during the antiretroviral era in South Africa: A systematic scoping review

2017

BACKGROUND: It is estimated that 650,000 patients may develop human immunodeficiency virus (HIV)-related renal disease in South Africa. South Africa has recently adopted WHO policy, stipulating that all HIV-infected patients...

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