Category Archives: Co-morbidities
Tenofovir-associated kidney disease in Africans: A systematic review
BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...
Factors associated with excess myocardial infarction risk in HIV-infected adults: A systematic review and meta-analysis
OBJECTIVES: To estimate the pooled relative risk of incident acute myocardial infraction (AMI) among HIV-infected adults compared to HIV-uninfected controls and explore the contribution of traditional and HIV-related risk factors....
Treatment outcomes of patients with localized anal squamous cell carcinoma according to HIV infection: Systematic review and meta-analysis
Background: Definitive chemoradiation (CRT) is the standard treatment for localized squamous cell carcinoma of the anus (SCCA). Because most phase III trials in SCCA have excluded patients with HIV, the...
Effects of aerobic and resistance exercise on cardiovascular parameters for people living with HIV: A meta-analysis
People living with HIV (PLWH) have limited exercise capacity because of anemia, neuromuscular disorders, and pulmonary limitations. We used a meta-analysis to examine the effect of aerobic and resistance exercise...
Feasibility of integrated, multilevel care for cardiovascular diseases (CVD) and HIV in low- and middle-income countries (LMICs): A scoping review
BACKGROUND: Integrated cardiovascular disease (CVD) and HIV (CVD-HIV) care interventions are being adopted to tackle the growing burden of noncommunicable diseases (NCDs) in low-and middle-income countries (LMICs) but there is...
Prevalence and incidence of new-onset seizures and epilepsy in patients with human immunodeficiency virus (HIV): Systematic review and meta-analysis
BACKGROUND: The prevalence and incidence of seizures are substantially higher in patients with human immunodeficiency virus (HIV) compared with the general population and is associated with higher mortality rates. Despite...
Prevalence of metabolic syndrome among HIV-positive and HIV-negative populations in sub-Saharan Africa – A systematic review and meta-analysis
BACKGROUND: Metabolic syndrome (MetS) is a constellation of conditions that increase the risk of cardiovascular diseases. It is an emerging concern in sub-Saharan African (SSA) countries, particularly because of an...
Residual or recurrent precancerous lesions after treatment of cervical lesions in HIV-infected women: A systematic review and meta-analysis of treatment failure
Background: Screening and treating premalignant cervical lesions (CIN2+) is an effective way to prevent cervical cancer, and recommendations exist for monitoring of treatment success. Yet, there is no specific recommendation...
Atrial fibrillation and human immunodeficiency virus type-1 infection: A systematic review. Implications for anticoagulant and antiarrhythmic therapy
The prevalence and incidence of atrial fibrillation/flutter (AF/AFL) in patients with human immunodeficiency virus type-1 (HIV-1) infection have been poorly investigated. We performed a systematic review using PubMed and Cochrane...
