Category Archives: Co-morbidities

Efficacy and safety of miconazole for oral candidiasis: A systematic review and meta-analysis

2016

The objective of this study is to assess the efficacy and safety of miconazole for treating oral candidiasis. Twelve electronic databases were searched for randomized controlled trials evaluating treatments for...

A systematic review of cardiovascular disease in sexual minorities

2017

BACKGROUND: Mental health and HIV disparities are well documented among sexual minorities, but there is a dearth of research on other chronic conditions. Cardiovascular disease remains the leading cause of...

The causative agents in infective endocarditis: A systematic review comprising 33,214 cases

2016

Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological...

Pre-conception counselling for key cardiovascular conditions in Africa: Optimising pregnancy outcomes

2016

The World Health Organisation (WHO) supports pre-conception care (PCC) towards improving health and pregnancy outcomes. PPC entails a continuum of promotive, preventative and curative health and social interventions. PPC identifies...

Hepatitis C virus coinfection as a risk factor for osteoporosis and fracture

2016

PURPOSE OF REVIEW: With increased survival of HIV-infected patients, osteoporotic fractures have developed as a major cause of morbidity in these patients, and chronic hepatitis C virus (HCV) coinfection has...

HIV and men

2016

INTRODUCTION: Since the initial description of HIV and AIDS, monumental efforts have been made both in the developed and developing countries to devise strategies and medications to control the disease....

Respiratory symptoms in people living with HIV and the effect of antiretroviral therapy: A systematic review and meta-analysis

2017

BACKGROUND: Antiretroviral therapy (ART) has significantly altered the pattern of acute and chronic HIV-related disease. However, it is not clear what this means in terms of respiratory symptoms. We sought...

Association between immune markers and surrogate markers of cardiovascular disease in HIV positive patients: A systematic review

2017

BACKGROUND: HIV infection is associated with an increased risk of cardiovascular disease (CVD). Chronic low-grade immune activation is likely one of the driving mechanisms. This systematic review provides an overview...

Diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome patients with intracranial lesions: Systematic review and meta-analysis

2016

OBJECTIVE: To evaluate the diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome (AIDS) patients with intracranial lesions via meta-analysis. METHODS: Relevant cohort studies were identified through...

Association between diabetes mellitus and active tuberculosis in Africa and the effect of HIV

2017

OBJECTIVE: To determine current evidence for the association between diabetes and active tuberculosis in Africa, and how HIV modifies, or not, any association between diabetes and active tuberculosis. METHODS: We...

Efficacy of nystatin for the treatment of oral candidiasis: A systematic review and meta-analysis

2016

OBJECTIVE: To systematically review and assess the efficacy, different treatment protocols (formulation, dosage, and duration), and safety of nystatin for treating oral candidiasis. METHODS: Four electronic databases were searched for...

Bone health and HIV in resource-limited settings: A scoping review

2016

PURPOSE OF REVIEW: Sub-Saharan Africa and other resource-limited settings (RLS) bear the greatest burden of the HIV epidemic globally. Advantageously, the expanding access to antiretroviral therapy (ART) has resulted in...

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