Category Archives: Co-morbidities
Systematic review on cumulative HIV viraemia among people living with HIV receiving antiretroviral treatment and its association with mortality and morbidity
BACKGROUND: We performed a systematic review to generate evidence on the association between cumulative human immunodeficiency virus (HIV) viraemia and health outcomes. METHODS: Quantitative studies reporting on HIV cumulative viraemia...
The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...
Prevalence and factors associated with hypertension among peoples living with HIV in East Africa, a systematic review and meta-analysis
Background In recent years, improved access to effective antiretroviral therapy has meant that people living with human immune virus are living longer than before. The burden of non-communicable diseases particularly,...
Prevalence and impact of HIV infections in patients with rheumatic heart disease: A systematic review and meta-analysis
Socioeconomic factors such as poor health and poor nutrition in low- and middle-income countries (LMICs) may favour inflammatory reactions, thus contributing to the recurrence of rheumatic fever (RF) and thereby...
Extracorporeal life support for patients with newly diagnosed HIV and acute respiratory distress syndrome: A systematic review and analysis of individual patient data
Extracorporeal membrane oxygenation (ECMO) may improve survival in patients with severe acute respiratory distress syndrome (ARDS). However, presence of immunosuppression is a relative contraindication for ECMO, which is withheld in...
The risk of new heart failure associated with protease inhibitor: Systematic scoping review
BACKGROUND: Protease inhibitors (PIs) have contributed to the long-term survival of persons with human immunodeficiency virus (PHIV). While there is a concern linking protease inhibitors to an increased risk of...
Fecal microbiota transplantation in human immunodeficiency virus-infected patient population: A systematic review and meta-analysis
BACKGROUND: Patients with human immunodeficiency virus (HIV) infection suffer from alterations in gut microbiota due to recurrent gastrointestinal infections and systemic inflammation. Fecal microbiota transplantation (FMT) appears to be a...
The use of non-invasive imaging modalities for the assessment of skeletal muscle quantity and quality in people with HIV: A narrative review
BACKGROUND: People with HIV (PWH) are prone to mobility impairments and physical dysfunction, with the loss of skeletal muscle quantity and quality being a major contributor to the dysfunction. Assessment...
The association between HIV infection and precancerous cervical lesion. A systematic review and meta-analysis of case-control studies
BACKGROUND: The effect of human immunodeficiency virus (HIV) on precancerous cervical lesion is not consistent across studies. Besides to the variability in the presence of a significant association between HIV...
Microbiological study of periodontal disease in populations with HIV: A systematic review and meta-analysis
BACKGROUND: No systematic review/meta-analysis has been conducted on the microbiological profile associated with the occurrence of periodontitis in patients with HIV. The aim of this study was to evaluate the...
