Category Archives: Co-morbidities

Treatment of severe or progressive Kaposi’s sarcoma in HIV-infected adults

2014

Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART),...

Might infection explain the higher risk of coronary heart disease in South Asians? Systematic review comparing prevalence rates with white populations in developed countries

2012

OBJECTIVES: South Asians in developed countries such as the UK are at comparatively high risk of coronary heart disease for reasons which are not fully understood. One unexplored hypothesis is...

End of life care in sub-Saharan Africa: A systematic review of the qualitative literature

2011

Background. End of life (EoL) care in sub-Saharan Africa still lacks the sound evidence-base needed for the development of effective, appropriate service provision. It is essential to make evidence from...

Anal intraepithelial neoplasia in HIV positive people

2001

OBJECTIVE: To review the current literature on HIV associated anal intraepithelial neoplasia (AIN). METHODS: A comprehensive Medline/Pubmed search was performed for the years 1980-2001 (January) for articles pertaining to HIV...

Incidence and progression of cervical lesions in women with HIV: A systematic global review

2014

Global data on cervical lesion incidence and progression in HIV-positive women are essential for understanding the natural history of cervical neoplasia and informing screening policy. A systematic review was performed...

Micronutrient supplementation in children and adults with HIV infection

2010

BACKGROUND: Micronutrient deficiencies are widespread and compound the effects of HIV disease; micronutrient supplements may be effective and safe in reducing this burden. OBJECTIVES: To assess whether micronutrient supplements are...

Non-clinical outcomes of antiretroviral therapy for HIV/AIDS in developing countries: A systematic literature review

2008

The impacts of antiretroviral therapy on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured....

Vertically acquired paediatric HIV infection: the challenges of providing comprehensive packages of care in resource-limited settings

2008

The successes achieved in paediatric disease management in well-resourced countries in recent years highlight the vast divide between the care options, and ultimately survival, between developed and developing areas of...

Pharmacological interventions for pruritus in adult palliative care patients

2013

Background: Pruritus is not the most prevalent but one of the most puzzling symptoms in palliative care patients. It can cause considerable discomfort and has a major impact on patients?...

Surgery in Castleman’s disease: A systematic review of 404 published cases

2012

We undertook a systematic review of 404 published cases of Castleman’s disease to identify the role of the surgeon beyond assistance in tissue-based diagnosis. Castleman’s disease is a rare primary...

What palliative care-related problems do patients experience at HIV diagnosis? A systematic review of the evidence

2011

CONTEXT: Palliative care is an essential element of HIV care throughout the disease trajectory, but there is a lack of information to guide clinical care at HIV diagnosis. OBJECTIVES: This...

Drug-related hypertension and resistance to antihypertensive treatment: A call for action

2011

Several drugs can cause hypertension and/or blunt the effect of antihypertensive treatment. They can exacerbate a previously well controlled hypertension and/or render it resistant to therapy. Accordingly, drugs represent a...

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