Category Archives: Co-morbidities
A systematic review of the effect of HIV infection and antiretroviral therapy on the risk of pre-eclampsia
BACKGROUND: The associations between HIV infection, antiretroviral therapy (ART), and pre-eclampsia are unclear. OBJECTIVES: To summarize research and clarify the implications of HIV and ART on pre-eclampsia risk. SEARCH STRATEGY:...
Evaluation of health disparity in bacterial vaginosis and the implications for HIV-1 acquisition in African American women
There is a health disparity for both bacterial vaginosis (BV) and human immunodeficiency virus type 1 (HIV-1) infection in African American women that may be linked. The evidence that BV...
Reversing gut damage in HIV infection: Using non-human primate models to instruct clinical research
Antiretroviral therapy (ART) has led to dramatic improvements in the lives of HIV-infected persons. However, residual immune activation, which persists despite ART, is associated with increased risk of non-AIDS morbidities....
Prevalence and distribution of non-AIDS causes of death among HIV-infected individuals receiving antiretroviral therapy: A systematic review and meta-analysis
The advent of antiretroviral therapy has significantly improved AIDS-related morbidity and mortality. Yet, among people living with HIV, deaths due to non-AIDS-defining illnesses have been on the rise. The objective...
Cerebral aneurysms associated with human immunodeficiency virus in adults: Literature review and new perspectives
INTRODUCTION: the treatment of human immunodeficiency virus (HIV) infection has been decreasing patient morbidity and mortality by opportunistic infections and, thus, survival has increased. This new reality has been changing...
Mapping the epidemiology of Kaposi Sarcoma and non-Hodgkin lymphoma among children in Sub-Saharan Africa: A review
Children with human immunodeficiency virus (HIV) have an increased risk of developing Kaposi Sarcoma (KS) and non-Hodgkin lymphoma (NHL) compared to HIV-negative children. We compiled currently published epidemiologic data on...
Treatment of multicentric Castleman’s disease in HIV-1 infected and uninfected patients: A systematic review
BACKGROUND: Multicentric Castleman’s disease (MCD) is frequently associated with human-herpesvirus (HHV)-8, especially in human immunodeficiency virus (HIV)-1 co-infections. The optimal treatment is unclear. This systematic review provides an overview of...
Disability and HIV: A systematic review and a meta-analysis of the risk of HIV infection among adults with disabilities in Sub-Saharan Africa
More than one billion people worldwide are estimated to be living with a disability. A significant proportion of them lives in Sub-Saharan Africa where they are reported to be at...
Evidence of increased blood pressure and hypertension risk among people living with HIV on antiretroviral therapy: A systematic review with meta-analysis
Owing to antiretroviral drug-induced endothelial dysfunction, HIV-infected patients on antiretroviral therapy (ART) may have elevated blood pressure. We conducted a systematic review and meta-analysis to estimate the effects of ART...
