Category Archives: Co-morbidities

Pharmacologic therapy for HIV-associated lipodystrophy

2004

OBJECTIVE: To evaluate the efficacy and safety of pharmacologic therapy in the treatment of HIV-associated lipodystrophy, with a focus on the treatment of fat redistribution. Drug therapies that have been...

Castleman’s disease: Systematic analysis of 416 patients from the literature

2011

BACKGROUND: Castleman’s disease is a rare primary disease of the lymph nodes with limited available clinical information. METHODS: A systematic literature search identified 416 cases amenable to detailed analysis. RESULTS:...

Omega-3 fatty acids and hypertriglyceridemia in HIV-infected subjects on antiretroviral therapy: Systematic review and meta-analysis

2011

PURPOSE: Antiretroviral therapy (ART) changed the course of AIDS. However, it has been associated with chronic metabolic complications including hypertriglyceridemia. The aim of this systematic review is to evaluate the...

Cannabinoids for treatment of chronic non-cancer pain: A systematic review of randomized trials

2011

Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in...

Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: A meta-analysis

2008

Objectives: To estimate stage-specific transition probabilities in individuals coinfected with HIV and hepatitis C virus (HCV), to examine the effect of covariates on these rates, and to investigate the effect...

HIV-associated intracranial aneurysmal vasculopathy in adults

2010

Diffuse fusiform intracranial aneurysms have been reported in children with human immunodeficiency virus (HIV) for over 2 decades, but have only recently been reported in adults with HIV. Although these...

Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis c patients: A systematic review and meta-analysis

2012

Background: There is a significant association between effects of interferon-alpha treatment and the risk of developing hyperglycemia in patients with chronic hepatitis C virus (HCV) infection. The objective of this...

Antimotility agents for chronic diarrhoea in people with HIV/AIDS

2008

BACKGROUND: AIDS-related diarrhoea is a common cause of morbidity and mortality in HIV positive individuals, especially in the sub-Saharan Africa where 70% of deaths from HIV occur. It often compromises...

Epidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: A comprehensive review

2009

OBJECTIVES: To identify the gaps of knowledge and highlight the challenges and opportunities for controlling cervical cancer in sub-Saharan Africa (SSA). METHODS: A comprehensive review of peer-reviewed literature to summarize...

Hepatitis C virus infection and risk of coronary artery disease: A systematic review of the literature

2012

Background: Several chronic infections have been associated with cardiovascular diseases, including Chlamydia pneumoniae, human immunodeficiency virus and viral hepatitis. This review evaluates the literature on the association between chronic hepatitis...

Relative risk of renal disease among people living with HIV: A systematic review and meta-analysis

2012

Antiretroviral therapy (ART) has substantially decreased mortality and HIV-related morbidity. However, other morbidities appear to be more common among PLHIV than in the general population. This study aimed to estimate...

Prevalence and outcomes of anemia in individuals with human immunodeficiency virus: A systematic review of the literature

2004

In patients with human immunodeficiency virus (HIV), anemia is a commonly encountered hematologic abnormality that has a significant impact on clinical outcomes and quality of life (QOL). This review describes...

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