Category Archives: Co-morbidities

Update on metabolic issues in HIV patients

2014

PURPOSE OF REVIEW: To report on the recent advances on lipids, diabetes, and body fat in HIV-infected patients from the perspective of aging. RECENT FINDINGS: HIV infection causes microbial translocation...

The risk of non-melanoma skin cancer in HIV-infected patients: New data and meta-analysis

2015

BACKGROUND: The role of HIV/AIDS in non-melanoma skin cancer is not well defined. OBJECTIVES: We sought to update the evidence of the association between HIV/AIDS and risk of non-melanoma skin...

Is the atherosclerotic process accentuated under conditions of HIV infection, antiretroviral therapy, and protease inhibitor exposure? Meta-analysis of the markers of arterial structure and function

2015

OBJECTIVE: To evaluate the apparent association of human immunodeficiency virus (HIV) infection, antiretroviral therapy (ART), and protease inhibitor (PI) exposure with the functional and structural markers of vasculature. METHODS: A...

A systematic review of the effects of visual inspection with acetic acid, cryotherapy, and loop electrosurgical excision procedures for cervical dysplasia in HIV-infected women in low- and middle-income countries

2015

BACKGROUND: Cervical cancer, almost all of which is caused by human papillomavirus, accounts for 12% of female cancers worldwide and is more common among HIV-infected women. Nine of 10 deaths...

Regional and national guideline recommendations for digital ano-rectal examination as a means for anal cancer screening in HIV positive men who have sex with men: A systematic review

2014

BACKGROUND: Although anal cancer is common in HIV positive men who have sex with men, few centres offer systematic screening. Regular digital ano-rectal examination (DARE) is a type of screening...

Long-term immune responses to vaccination in HIV-infected patients: A systematic review and meta-analysis

2014

Vaccine-induced antibodies may wane more quickly in persons living with human immunodeficiency virus (HIV) than in healthy individuals. We reviewed the literature on vaccines routinely recommended in HIV-infected patients to...

HIV, antiretroviral therapy, and hypertensive disorders in pregnancy: A systematic review and meta-analysis

2015

BACKGROUND: There are data to suggest that infection with HIV or use of highly active antiretroviral therapy increases the risk of hypertensive disorders in pregnancy. This systematic review and meta-analysis...

Optimal management of cervical cancer in HIV-positive patients: A systematic review

2015

The clinical management of cervical cancer in HIV-positive patients has challenges mainly due to the concerns on immune status. At present, their mode of management is similar to HIV-seronegative patients...

Is there enough evidence to use bisphosphonates in HIV-infected patients? A systematic review and meta-analysis

2014

An increased prevalence of osteopenia and osteoporosis has been observed in HIV-infected cohorts. We investigated the effect of bisphosphonates on bone mineral density in adults with HIV infection. Outcomes of...

Hepatitis C virus increases the risk of kidney disease among HIV-positive patients: Systematic review and meta-analysis

2016

BACKGROUND: Kidney disease has become an important co-morbidity among human immunodeficiency virus-infected patients as they live longer in the era of highly effective antiretroviral therapy. It remains unclear how co-infection...

HIV infection and cardiovascular disease

2014

AIMS: With the success of antiretroviral therapy (ART), non-human immunodeficiency virus (HIV)-related comorbidities like cardiovascular diseases (CVDs) are of increasing concern. We describe important recent research developments on the epidemiology...

Discontinuation of tenofovir disoproxil fumarate for presumed renal adverse events in treatment-naïve HIV-1 patients: Meta-analysis of randomized clinical studies

2014

Background: Safety and efficacy of tenofovir disoproxil fumarate (TDF) as a component of antiretroviral therapy (ART) have been demonstrated in clinical trials. TDF nephrotoxicity has been reported in both HIV-infected...

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