Category Archives: Co-morbidities
Systematic review of prevalence and predictors of frailty in individuals with human immunodeficiency virus
OBJECTIVES: To describe the prevalence and predictors of frailty in individuals with the human immunodeficiency virus (HIV) using systematic review methodology. DESIGN: Review. SETTING: Community. PARTICIPANTS: Older adults with HIV....
Ambulatory blood pressure monitoring in individuals with HIV: A systematic review and meta-analysis
INTRODUCTION: Abnormal diurnal blood pressure (BP) rhythms may contribute to the high cardiovascular disease risk in HIV-positive (HIV+) individuals. To synthesize the current literature on ambulatory BP monitoring (ABPM) in...
Reversing gut damage in HIV infection: Using non-human primate models to instruct clinical research
Antiretroviral therapy (ART) has led to dramatic improvements in the lives of HIV-infected persons. However, residual immune activation, which persists despite ART, is associated with increased risk of non-AIDS morbidities....
Pro-inflammatory markers in relation to cardiovascular disease in HIV infection. A systematic review
BACKGROUND: In the past years many inflammatory markers have been studied in association with clinically manifest cardiovascular disease (CVD) and carotid intima-media thickness (CIMT) in HIV-infected patients, to obtain insights...
Cerebral aneurysms associated with human immunodeficiency virus in adults: Literature review and new perspectives
INTRODUCTION: the treatment of human immunodeficiency virus (HIV) infection has been decreasing patient morbidity and mortality by opportunistic infections and, thus, survival has increased. This new reality has been changing...
Prevalence and distribution of non-AIDS causes of death among HIV-infected individuals receiving antiretroviral therapy: A systematic review and meta-analysis
The advent of antiretroviral therapy has significantly improved AIDS-related morbidity and mortality. Yet, among people living with HIV, deaths due to non-AIDS-defining illnesses have been on the rise. The objective...
Mapping the epidemiology of Kaposi Sarcoma and non-Hodgkin lymphoma among children in Sub-Saharan Africa: A review
Children with human immunodeficiency virus (HIV) have an increased risk of developing Kaposi Sarcoma (KS) and non-Hodgkin lymphoma (NHL) compared to HIV-negative children. We compiled currently published epidemiologic data on...
Risk of intracerebral hemorrhage in HIV/AIDS: A systematic review and meta-analysis
Evidence for the association and the increased risk of stroke with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is growing. Recent studies have reported on HIV infection as a potent risk...
A systematic review of the effect of HIV infection and antiretroviral therapy on the risk of pre-eclampsia
BACKGROUND: The associations between HIV infection, antiretroviral therapy (ART), and pre-eclampsia are unclear. OBJECTIVES: To summarize research and clarify the implications of HIV and ART on pre-eclampsia risk. SEARCH STRATEGY:...
Comparative safety and efficacy of statins for primary prevention in human immunodeficiency virus-positive patients: A systematic review and meta-analysis
The efficacy and safety of different statins for human immunodeficiency virus (HIV)-positive patients in the primary prevention setting remain to be established. In the present meta-analysis, 18 studies with 736...
