Category Archives: Co-morbidities
A review of the efficacy and outcomes studies of currently approved chemotherapy treatments for advanced AIDS-Kaposi’s sarcoma
Background: Acquired Immune Deficiency Syndrome (AIDS) – related Kaposi’s sarcoma (KS) is a rare aggressive tumor. The benefits of drug therapy are established by clinical trials but it has been...
Interventions for previously untreated patients with AIDS-associated Non-Hodgkin’s Lymphoma
BACKGROUND: Human immunodeficiency virus (HIV) infection is known to be associated with an increased risk of non-Hodgkin’s lymphoma (NHL). The majority of lymphomas (>80%) occurring during immunosuppression are aggressive B-cell...
The safety and effectiveness of statins as treatment for HIV-dyslipidemia: The evidence so far and the future challenges
Introduction: Statin therapy is widely used across the globe for the treatment and prevention of cardiovascular disease (CVD). It is well established that statin therapy is associated with significant decrease...
The management of dyslipidaemias in antiretroviral-treated HIV infection: A systematic review
OBJECTIVES: The aim of the study was to assess the currently available evidence concerning the management of dyslipidaemias in HIV-infected individuals treated with antiretroviral therapy. METHODS: Randomized trials, published within...
Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: A systematic review
BACKGROUND: The clinical course of diverticular disease in immunosuppressed patients is widely believed to be more severe than in the general population. In this study we systematically reviewed the literature...
Neurocognitive impairment in HIV-1-infected adults in Sub-Saharan Africa: A systematic review and meta-analysis
OBJECTIVE: To estimate the burden of HIV neurocognitive impairment (NCI) among adult patients on and off antiretroviral therapy (ART) in Sub-Saharan Africa. METHODS: Estimates were derived from a random effects...
Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: A systematic review
HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated...
The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS
BACKGROUND: The use of cannabis (marijuana) or of its psychoactive ingredient delta-9-tetrahydrocannabinol (THC) as a medicine has been highly contested in many settings.There have been claims that smoked or ingested...