Category Archives: Co-morbidities
Role of recombinant human growth hormone in HIV-associated wasting and cachexia: Pathophysiology and rationale for treatment
Background: Wasting, or cachexia, is a significant, debilitating, and potentially life-threatening complication of HIV infection. It is associated with reduced strength and functional ability, reduced ability to with stand opportunistic...
Management of HIV-associated tuberculosis in resource-limited settings: A state-of-the-art review
The HIV-associated tuberculosis (TB) epidemic remains a huge challenge to public health in resource-limited settings. Reducing the nearly 0.5 million deaths that result each year has been identified as a...
Systematic review of vestibular disorders related to human immunodeficiency virus and acquired immunodeficiency syndrome
INTRODUCTION: Disorders of the auditory and vestibular system are often associated with human immunodeficiency virus infection and acquired immunodeficiency syndrome. However, the extent and nature of these vestibular manifestations are...
Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa
Two-thirds of the world’s HIV-infected people live in sub-Saharan Africa, and more than 1.5 million of them die annually. As access to antiretroviral treatment has expanded within the region; early...
Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review
Background: Since the mid-1990s, there have been growing efforts to prevent cervical cancer in less-developed countries through the development of innovative screening approaches such as visual inspection of the cervix...
Comparative incidence of cancer in HIV-AIDS patients and transplant recipients
Background: Studies have found a relationship between decreased immunity and increased incidence of cancer. Methods: A systematic review of observational studies evaluating the incidence of cancer in both organ recipients...
Might infection explain the higher risk of coronary heart disease in South Asians? Systematic review comparing prevalence rates with white populations in developed countries
OBJECTIVES: South Asians in developed countries such as the UK are at comparatively high risk of coronary heart disease for reasons which are not fully understood. One unexplored hypothesis is...
Cotrimoxazole for prophylaxis or treatment of opportunistic infections of HIV/AIDS in patients with previous history of hypersensitivity to cotrimoxazole
BACKGROUND: Opportunistic infections continue to cause a significant amount of morbidity and mortality worldwide in patients infected with HIV. Trimethoprim-sulfamethoxazole (cotrimoxazole) is used in the treatment and prophylaxis of several...
Iron deficiency in children with HIV-associated anaemia: A systematic review and meta-analysis
We conducted a systematic review and meta-analysis to determine the prevalence of iron deficiency in HIV-infected children from high- and low-income settings and compared it with that of HIV-uninfected controls....
