Category Archives: Co-morbidities

Drug-related hypertension and resistance to antihypertensive treatment: A call for action

2011

Several drugs can cause hypertension and/or blunt the effect of antihypertensive treatment. They can exacerbate a previously well controlled hypertension and/or render it resistant to therapy. Accordingly, drugs represent a...

Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy

2007

Although antiretroviral therapy (ART) is critical for preventing mother-to-child transmission of HIV, concern has been raised about the possibility that it may cause mitochondrial dysfunction in infants. There is adequate...

Anabolic steroids for the treatment of weight loss in HIV-infected individuals

2005

BACKGROUND: Individuals with HIV infection often lose weight during the course of their disease. Furthermore, low serum concentrations of testosterone are common in individuals with HIV infection, particularly those with...

Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: A meta-analysis

2001

Studies have shown that rates of liver disease are higher in persons who are coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) than they are in persons...

Pharmacological treatment of painful HIV-associated sensory neuropathy: A systematic review and meta-analysis of randomised controlled trials

2010

BACKGROUND: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects ~40% of HIV infected individuals treated with antiretroviral therapy (ART). The prevalence of HIV-SN has increased despite the more widespread use...

Incident fractures in HIV-infected individuals: A systematic review and meta-analysis

2013

OBJECTIVE(S): Some but not all studies indicate that individuals with HIV infection are at an increased risk of fracture. We systematically reviewed the literature to investigate whether incidence of fracture...

The impact of hepatitis C virus coinfection on HIV-related kidney disease: A systematic review and meta-analysis

2008

BACKGROUND: In the era of antiretroviral therapy, non-AIDS complications such as kidney disease are important contributors to morbidity and mortality. OBJECTIVE: To estimate the impact of hepatitis C coinfection on...

The frequency and significance of Iron-Deficiency anemia in patients with selected concurrent illness

2008

Approximately 30% of the world’s population is anemic, of which 50% is iron deficiency anemia (IDA). The extent to which IDA affects patients with concomitant illness has not been described.A...

Systematic review of orogenital HIV-1 transmission probabilities

2008

BACKGROUND: The objective was to assess the risk of HIV transmission from orogenital intercourse (OI). METHODS: Systematic review of the literature on HIV-1 infectiousness through OI conducted according to MOOSE...

Potential benefits of carnitine in HIV-positive patients

2012

Carnitine is a nonessential amino acid that has a central role in lipid peroxidation and mitochondrial metabolism. Carnitine deficiency is rare in adult human subjects who have a normal diet...

What palliative care-related problems do patients experience at HIV diagnosis? A systematic review of the evidence

2011

CONTEXT: Palliative care is an essential element of HIV care throughout the disease trajectory, but there is a lack of information to guide clinical care at HIV diagnosis. OBJECTIVES: This...

Antihypertensive drugs in patients treated with antiretrovirals

2012

OBJECTIVE: To review the literature for information regarding pharmacokinetic interactions between antiretrovirals and antihypertensive agents, evaluate the clinical significance of these interactions, and analyze the effect of antihypertensive drugs on...

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