Category Archives: Co-morbidities

Iron deficiency in children with HIV-associated anaemia: A systematic review and meta-analysis

2012

We conducted a systematic review and meta-analysis to determine the prevalence of iron deficiency in HIV-infected children from high- and low-income settings and compared it with that of HIV-uninfected controls....

Evaluation and management of dyslipidemia in patients with HIV infection

2002

OBJECTIVE: Persons with HIV infection develop metabolic abnormalities related to their antiretroviral therapy and HIV infection itself. The objective of this study was to summarize the emerging evidence for the...

Role of the placenta in adverse perinatal outcomes among HIV-1 seropositive women

2013

Women seropositive for human immunodeficiency virus type 1 (HIV-1) are at an increased risk for a number of adverse perinatal outcomes. Although efforts to reduce mother-to-child transmission of HIV (MTCT)...

HIV and the risk of direct obstetric complications: A systematic review and meta-analysis

2013

BACKGROUND: Women of reproductive age in parts of sub-Saharan Africa are faced both with high levels of HIV and the threat of dying from the direct complications of pregnancy. Clinicians...

Interventions for HIV-associated nephropathy

2013

BACKGROUND: Human immunodeficiency virus-associated nephropathy (HIVAN) is the most common cause of end stage kidney disease (ESKD) in human immunodeficiency virus-1 (HIV-1) serotype patients and it mostly affects patients of...

Predictors and treatment strategies of HIV-related fatigue in the combined antiretroviral therapy era

2010

Objective: To assess predictors and reported treatment strategies of HIV-related fatigue in the combined antiretroviral (cART) era. Method: Five databases were searched and reference lists of pertinent articles were checked....

HIV-associated anemia in children: A systematic review from a global perspective

2008

Objectives:: To assess the importance of anemia in HIV-infected children in western and tropical settings. Design:: A systematic review with a descriptive component. Methods:: Four databases were searched and reference...

Osteoporosis and vitamin D deficiency in HIV-positive patients

2011

Objective: To review the epidemiology and pathophysiology of osteoporosis in patients with HIV infection and discuss vitamin D deficiency and the treatment of HIV-positive patients with osteoporosis. Data Sources: A...

A review of premature frailty in HIV-infected persons; another manifestation of HIV-related accelerated aging

2011

PURPOSE: HIV-related immunological and multisystem accelerated aging contributes to the premature occurrence of age-related comorbidities. Such non-AIDS-defining comorbidities include cardiovascular disease, dyslipidemia, osteoporosis and frailty, and are of increasing importance...

Treatment of severe or progressive Kaposi’s sarcoma in HIV-infected adults

2014

Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART),...

Drug-related hypertension and resistance to antihypertensive treatment: A call for action

2011

Several drugs can cause hypertension and/or blunt the effect of antihypertensive treatment. They can exacerbate a previously well controlled hypertension and/or render it resistant to therapy. Accordingly, drugs represent a...

Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy

2007

Although antiretroviral therapy (ART) is critical for preventing mother-to-child transmission of HIV, concern has been raised about the possibility that it may cause mitochondrial dysfunction in infants. There is adequate...

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