Category Archives: Co-morbidities
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
Growth hormone axis treatments for HIV-associated lipodystrophy: A systematic review of placebo-controlled trials
BACKGROUND: HIV-associated lipodystrophy is a disorder of fat metabolism that occurs in patients with HIV infection. It can cause metabolic derangements and negative self-perceptions of body image, and result in...
Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review
AIM: To investigate the diagnosis, pathogenesis, natural history, and management of nodular regenerative hyperplasia (NRH) in patients with human immunodeficiency virus (HIV). METHODS: We performed a systematic review of the...
Does epoetin alfa improve health-related quality of life in chronically ill patients with anemia: Summary of trials of cancer, HIV/AIDS, and chronic kidney disease
OBJECTIVES: Anemia, defined as having low levels of hemoglobin (HGB), is caused by disease-related (e.g., bone marrow suppression, nutritional deficiency) or treatment-related (e.g., chemotherapy, antiretroviral therapy) factors. Although epoetin alfa...
No relationship between TNF-alpha genetic variants and combination antiretroviral therapy-related lipodystrophy syndrome in HIV type 1-infected patients: A case-control study and a meta-analysis
Tumor necrosis factor alpha (TNF-alpha) is thought to be involved in the pathogenic and metabolic events associated with HIV-1 infection. We assessed whether carriage of the TNF-alpha gene promoter single...
Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis
BACKGROUND: Men who have sex with men (MSM) are at greatly increased risk of human papillomavirus (HPV)-associated anal cancer. Screening for the presumed cancer precursor, high-grade anal intraepithelial neoplasia (AIN),...
HIV positivity, protease inhibitor exposure and subclinical atherosclerosis: A systematic review and meta-analysis of observational studies
CONTEXT: Patients with HIV may have increased risk of atherosclerotic cardiovascular disease owing to multiple biological mechanisms. OBJECTIVE: To evaluate the evidence for subclinical atherosclerosis among patients with HIV. DESIGN:...