Category Archives: Co-morbidities
Mannose-binding lectin and the risk of HIV transmission and disease progression in children: A systematic review
BACKGROUND: Mannose-binding lectin (MBL) can activate the complement system by binding to carbohydrates, such as those presented on the HIV virion surface. It is unclear whether genetically determined MBL deficiency...
A systematic review of permanent and semipermanent dermal fillers for HIV-associated facial lipoatrophy
The objective of this study was to assess the safety and efficacy of injectable semipermanent and permanent dermal fillers, compared to other facial augmentation techniques, for the management of facial...
Efficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: Systematic review
Objectives To determine the efficacy and safety of zinc supplementary in children, adults and pregnant women with HIV infection. Methods We conducted a comprehensive search in Medline, Embase, the Cochrane...
Adjunctive corticosteroids for Pneumocystis Jiroveci Pneumonia in patients with HIV-infection
BACKGROUND: Pneumocystis jiroveci pneumonia (PCP) remains the most common opportunistic infection in patients infected with the human immunodeficiency virus (HIV). Among patients with HIV infection and PCP the mortality rate...
A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals
OBJECTIVE: To estimate summary standardized incidence ratios (SIRs) of non-AIDS cancers among HIV-infected individuals compared with general population rates overall and stratified by gender, AIDS, and highly active antiretroviral therapy...
Relative risk of cardiovascular disease among people living with HIV: A systematic review and meta-analysis
OBJECTIVES: The aim of this study was to estimate the relative risk of cardiovascular disease (CVD) among people living with HIV (PLHIV) compared with the HIV-uninfected population. METHODS: We conducted...
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
Growth hormone axis treatments for HIV-associated lipodystrophy: A systematic review of placebo-controlled trials
BACKGROUND: HIV-associated lipodystrophy is a disorder of fat metabolism that occurs in patients with HIV infection. It can cause metabolic derangements and negative self-perceptions of body image, and result in...
