Category Archives: Co-morbidities

Topical treatment of anogenital human papillomavirus infection in male patients

2009

Background: Human papillomavirus (HPV) -associated anogenital warts have a prevalence of up to 78% in sexually active men. Some HPV subtypes bear a considerable oncogenic potential. Materials & methods: Original...

Progressive resistive exercise interventions for adults living with HIV/AIDS

2007

BACKGROUND: Due to medical advancements, many people living with HIV infection in developed countries are living longer (Palella 1998). HIV infection can now present as a chronic illness with an...

Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis

2012

BACKGROUND: Men who have sex with men (MSM) are at greatly increased risk of human papillomavirus (HPV)-associated anal cancer. Screening for the presumed cancer precursor, high-grade anal intraepithelial neoplasia (AIN),...

Aerobic exercise interventions for adults living with HIV/AIDS

2010

BACKGROUND: Access to combination antiretroviral therapy has turned HIV into a chronic and manageable disease for many. This increased chronicity has been mirrored by increased prevalence of health-related challenges experienced...

Health-related quality of life assessment in adult haemophilia patients: A systematic review and evaluation of instruments

2003

The objective of this study was to review and evaluate the performance of health-related quality of life (HRQL) and other health status measures used in studies of adult haemophilia and...

Megestrol acetate for the treatment of anorexia-cachexia syndrome

2005

BACKGROUND: Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer-associated anorexia. In 1993 MA was approved by the USA’s Federal Drug Administration for the...

A systematic review of risk factors for death in adults during and after tuberculosis treatment

2011

BACKGROUND: Despite effective anti-tuberculosis chemotherapy, case-fatality rates of up to 25% are described in both industrialised and resource-poor settings. An understanding of the factors predisposing to poor outcome may allow...

HIV infection and sexual risk behaviour among youth who have experienced orphanhood: Systematic review and meta-analysis

2011

BACKGROUND: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and...

Cannabinoids for treatment of chronic non-cancer pain: A systematic review of randomized trials

2011

Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in...

Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: A meta-analysis

2008

Objectives: To estimate stage-specific transition probabilities in individuals coinfected with HIV and hepatitis C virus (HCV), to examine the effect of covariates on these rates, and to investigate the effect...

HIV-associated intracranial aneurysmal vasculopathy in adults

2010

Diffuse fusiform intracranial aneurysms have been reported in children with human immunodeficiency virus (HIV) for over 2 decades, but have only recently been reported in adults with HIV. Although these...

Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis c patients: A systematic review and meta-analysis

2012

Background: There is a significant association between effects of interferon-alpha treatment and the risk of developing hyperglycemia in patients with chronic hepatitis C virus (HCV) infection. The objective of this...

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