Category Archives: Co-morbidities
Epidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: A comprehensive review
OBJECTIVES: To identify the gaps of knowledge and highlight the challenges and opportunities for controlling cervical cancer in sub-Saharan Africa (SSA). METHODS: A comprehensive review of peer-reviewed literature to summarize...
Efficacy of selected treatments of HIV wasting: A systematic review and meta-analysis
PURPOSE: To assess the efficacy of recombinant human growth hormone (rhGH), testosterone, and anabolic steroids in the treatment of HIV wasting. METHODS: A systematic review and meta-analysis of studies published...
A systematic review of psychological functioning of children exposed to HIV: Using evidence to plan for tomorrow’s HIV needs
Prevention of mother to child transmission of HIV can virtually eliminate paediatric HIV infection. Studies are needed to understand child development outcomes for children exposed to HIV in utero but...
Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: A systematic review and meta-analysis
In patients with HIV-1 infection who are starting combination antiretroviral therapy (ART), the incidence of immune reconstitution inflammatory syndrome (IRIS) is not well defined. We did a meta-analysis to establish...
Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials
OBJECTIVES: We performed a meta-analysis to assess the efficacy and safety of switching from protease inhibitor (PI)- to nevirapine (NVP)-based regimens in HIV-infected patients in whom virological suppression had been...
Second-line salvage treatment of AIDS-associated Pneumocystis jirovecii pneumonia: A case series and systematic review
Background: Limited clinical data exist to guide the choice of second-line salvage treatment for AIDS-associated Pneumocystis jirovecii pneumonia (PCP). Methods: We did a systematic search of MEDLINE for all randomized...
Treatment for leiomyosarcoma and leiomyoma in children with HIV infection
BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...
