Category Archives: Co-morbidities
Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: A meta-analysis of six prospective, randomized, comparative studies
Background: Hematologic changes that occur with HIV infection and antiretroviral therapy may impact the quality of life of patients and have been associated with morbidity and mortality. The management of...
Human T-lymphotropic virus/HIV co-infection: A clinical review
PURPOSE OF REVIEW: Human T-lymphotropic virus (HTLV)/HIV co-infections are often undiagnosed, with important clinical implications. The literature is relatively sparse with key observations derived in the pre-highly-active antiretroviral therapy era....
Protease inhibitors and avascular necrosis: A systematic review and meta-analysis
Avascular necrosis (AVN) is a pathological process associated with many medical conditions, including human immunodeficiency virus (HIV) infection. Whether or not the use of protease inhibitors (PIs) confers additional risk...
Isoniazid prophylaxis for tuberculosis in HIV infection: A meta-analysis of randomized controlled trials
OBJECTIVES: To evaluate the efficacy of isoniazid for the prevention of tuberculosis in tuberculin skin test-positive and negative individuals with HIV infection. DESIGN: Meta-analysis of randomized controlled trials. SETTING: Seven...
A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura
Treatment of childhood idiopathic thrombocytopenic purpura is still an area of controversy. We reviewed the literature on anti-D treatment. Most studies used intravenous anti-D. Single doses of 50 microg/kg increased...
Safety of hormonal and intrauterine methods of contraception for women with HIV/AIDS: A systematic review
OBJECTIVE: To determine from the literature whether HIV-infected women who use hormonal or intrauterine contraception are at increased risk of HIV disease progression, other adverse health outcomes, or HIV transmission...
Comparative incidence of cancer in HIV-AIDS patients and transplant recipients
Background: Studies have found a relationship between decreased immunity and increased incidence of cancer. Methods: A systematic review of observational studies evaluating the incidence of cancer in both organ recipients...
The safety and effectiveness of statins as treatment for HIV-dyslipidemia: The evidence so far and the future challenges
Introduction: Statin therapy is widely used across the globe for the treatment and prevention of cardiovascular disease (CVD). It is well established that statin therapy is associated with significant decrease...