Category Archives: Co-morbidities
Anabolic steroids for the treatment of weight loss in HIV-infected individuals
BACKGROUND: Individuals with HIV infection often lose weight during the course of their disease. Furthermore, low serum concentrations of testosterone are common in individuals with HIV infection, particularly those with...
Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: A meta-analysis
Studies have shown that rates of liver disease are higher in persons who are coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) than they are in persons...
Pharmacological treatment of painful HIV-associated sensory neuropathy: A systematic review and meta-analysis of randomised controlled trials
BACKGROUND: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects ~40% of HIV infected individuals treated with antiretroviral therapy (ART). The prevalence of HIV-SN has increased despite the more widespread use...
Incident fractures in HIV-infected individuals: A systematic review and meta-analysis
OBJECTIVE(S): Some but not all studies indicate that individuals with HIV infection are at an increased risk of fracture. We systematically reviewed the literature to investigate whether incidence of fracture...
The impact of hepatitis C virus coinfection on HIV-related kidney disease: A systematic review and meta-analysis
BACKGROUND: In the era of antiretroviral therapy, non-AIDS complications such as kidney disease are important contributors to morbidity and mortality. OBJECTIVE: To estimate the impact of hepatitis C coinfection on...
Physical activity: Do patients infected with HIV practice? How much? A systematic review
Several studies have suggested that aerobic physical activity is safe and beneficial for HIV-infected adults. However, there is information lacking regarding whether HIV-infected patients practice physical activity and to what...
A review of premature frailty in HIV-infected persons; another manifestation of HIV-related accelerated aging
PURPOSE: HIV-related immunological and multisystem accelerated aging contributes to the premature occurrence of age-related comorbidities. Such non-AIDS-defining comorbidities include cardiovascular disease, dyslipidemia, osteoporosis and frailty, and are of increasing importance...
Treatment of severe or progressive Kaposi’s sarcoma in HIV-infected adults
Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART),...
Maternal infection and risk of preeclampsia: Systematic review and metaanalysis
There are lingering questions regarding the association between maternal infection and preeclampsia. Systematic review and metaanalysis was conducted of observational studies that examined the relationship between maternal infection and preeclampsia....
