Category Archives: Co-morbidities
Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers
Background: Extensive evidence shows that well over 50% of people prefer to be cared for and to die at home provided circumstances allow choice. Despite best efforts and policies, one-third...
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings
BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings....
Epidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: A comprehensive review
OBJECTIVES: To identify the gaps of knowledge and highlight the challenges and opportunities for controlling cervical cancer in sub-Saharan Africa (SSA). METHODS: A comprehensive review of peer-reviewed literature to summarize...
A literature review on cardiovascular risk in human immunodeficiency virus-infected patients: Implications for clinical management
INTRODUCTION: In recent years, there has been growing concern about an increasing rate of cardiovascular diseases in human immunodeficiency virus-infected patients, which could be associated with side effects of highly...
Incidence and progression of cervical lesions in women with HIV: A systematic global review
Global data on cervical lesion incidence and progression in HIV-positive women are essential for understanding the natural history of cervical neoplasia and informing screening policy. A systematic review was performed...
Micronutrient supplementation in children and adults with HIV infection
BACKGROUND: Micronutrient deficiencies are widespread and compound the effects of HIV disease; micronutrient supplements may be effective and safe in reducing this burden. OBJECTIVES: To assess whether micronutrient supplements are...
Non-clinical outcomes of antiretroviral therapy for HIV/AIDS in developing countries: A systematic literature review
The impacts of antiretroviral therapy on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured....
Vertically acquired paediatric HIV infection: the challenges of providing comprehensive packages of care in resource-limited settings
The successes achieved in paediatric disease management in well-resourced countries in recent years highlight the vast divide between the care options, and ultimately survival, between developed and developing areas of...