Category Archives: Co-morbidities

The challenge of AIDS-related malignancies in sub-Saharan Africa

2010

Background: With the lengthening of life expectancy among HIV-positive subjects related to the use of highly active antiretroviral treatments, an increased risk of cancer has been described in industrialized countries....

HIV positivity, protease inhibitor exposure and subclinical atherosclerosis: A systematic review and meta-analysis of observational studies

2009

CONTEXT: Patients with HIV may have increased risk of atherosclerotic cardiovascular disease owing to multiple biological mechanisms. OBJECTIVE: To evaluate the evidence for subclinical atherosclerosis among patients with HIV. DESIGN:...

Efficacy and safety of cesarean delivery for prevention of mother-to-child transmission of HIV-1

2005

BACKGROUND: Cesarean section before labor and before ruptured membranes (“elective cesarean section”, or ECS) has been introduced as an intervention for the prevention of mother-to-child transmission (MTCT) of HIV-1. The...

Endocrine and metabolic abnormalities among HIV-infected patients: A current review

2013

Multiple endocrine and metabolic abnormalities have been reported among human immunodeficiency virus (HIV) patients since the pre-antiretroviral therapy era. These abnormalities present with either subclinical or overt clinical features. Endocrine...

Treatment of Kaposi sarcoma in children with HIV-1 infection

2014

Background: Kaposi sarcoma (KS) remains the second most frequently diagnosed HIV-related malignancy (HRM) worldwide and most common HRM in sub-Saharan Africa where HIV is most prevalent and human herpesvirus 8...

Pulmonary tuberculosis in severely-malnourished or HIV-infected children with pneumonia: A review

2013

Presentation of pulmonary tuberculosis (PTB) as acute pneumonia in severely-malnourished and HIV-positive children has received very little attention, although this is very important in the management of pneumonia in children...

Flu and pneumococcal immunisations in HIV-infected children: Methodological quality of current recommendations

2011

OBJECTIVE: To assess the quality of guidelines, consensus statements and systematic reviews on flu and pneumococcal immunisations in HIV-infected children. METHOD: The authors screened PubMed and Embase databases until the...

Multicentric Castleman’s disease in HIV infection: A systematic review of the literature

2008

The objective of this study is to systematically review the epidemiology and the clinical and virologic aspects of multicentric Castleman’s disease in HIV-positive patients and to evaluate treatment strategies and...

Evidence behind the WHO guidelines: Hospital Care for Children: What is the aetiology and treatment of chronic diarrhoea in children with HIV?

2009

The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines,...

Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis

2010

The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...

Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: Systematic review and meta-analysis of randomized controlled trials

2010

OBJECTIVES: To compare lipid profiles in HIV-infected adults receiving atazanavir-based regimens. METHODS: We conducted a systematic review of randomized controlled trials (RCTs) comparing atazanavir or atazanavir/ritonavir with a comparator and...

Interventions for treating AIDS-associated Hodgkin’ s lymphoma in treatment-naive adults

2007

Background: Hodgkin’s disease (HD) is the most common non-AIDS-defining malignancy in HIV-infected patients. Its unusually aggressive tumour behaviour includes a higher frequency of unfavourable histologic subtypes, high-stage and extranodal involvement...

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