Category Archives: Co-morbidities
Economic evaluations of sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs): A systematic review
BACKGROUND: Sexual and reproductive health (SRH) programmes and services aim to prevent complications of pregnancy and childbirth, unintended pregnancies, unsafe abortions, complications caused by sexually transmitted infections, including HIV, sexual...
The prevalence of nonalcoholic fatty liver disease in people living with HIV: A systematic review and meta-analysis
Background: Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD...
Concomitant virus infection increases mortality and worsens outcome of acute pancreatitis: A systematic review and meta-analysis
BACKGROUND: Acute pancreatitis (AP) is a major health threat, with a high mortality rate in severe forms. Though alcohol and bile-induced factors are the most common causes, increasing evidence suggests...
The burden of HPV infections and HPV-related diseases among people with HIV: A systematic literature review
Human papillomavirus (HPV) is associated with a significant global burden of precancerous lesions and cancer. People with HIV (PWH) are at higher risk of HPV infection and HPV‐related diseases. This...
A systematic review of mediation analysis frameworks in studies examining the determinants of cardiometabolic outcomes in people living with HIV
Introduction Mediation analysis provides a more flexible mechanistic view of the causal relationship between HIV-related factors and cardiometabolic diseases. However, there is limited evidence on how mediation analysis is implemented...
Urgent focus on the surgical risks of people living with HIV: A systematic review and meta-analysis
With the widespread promotion and application of antiretroviral therapy in clinical practice, people living with HIV (PLWH) have the potential to live as long as non-HIV people and the probability...
Comprehensive coronary CT angiography in people living with HIV: A systematic review and meta-analysis
OBJECTIVES: People living with HIV (PLWH) were previously shown to have a higher prevalence of non-calcified coronary plaque with discrepant results for coronary stenosis and any plaque prevalence. This systematic...
Understanding HIV-exposed uninfected children: A narrative review
The widespread implementation of antiretroviral therapy has significantly reduced HIV-related mortality and mother-to-child transmission. Despite being HIV-uninfected, HIV-exposed children (HEU) seem to face heightened risks of immune dysfunction, cardiometabolic diseases,...
Causes of hospitalisation among people living with HIV worldwide, 2014-23: A systematic review and meta-analysis
Background: Despite improved access to antiretroviral therapy (ART), HIV-related morbidity and mortality remain high. A previous review (2007-14) found that AIDS-related illnesses were the leading causes of hospitalisations. We aimed to...
Growth of children who are HIV-exposed but uninfected: A systematic review and meta-analysis
BACKGROUND: Pooled analyses summarising long-term growth outcomes in children who are HIV-exposed uninfected (HEU) compared with children who are HIV-unexposed (HU) are lacking. We aimed to summarise the existing literature...
