Category Archives: Co-morbidities

Association of exposure to air pollutants and risk of mortality among people living with HIV: A systematic review

2024

Background People living with HIV (PLWH) are more vulnerable to infectious and non-infectious comorbidities due to chronic inflammation and immune dysfunction. Air pollution is a major global health risk, contributing...

Antiviral therapy for cytomegalovirus retinitis: A systematic review and meta-analysis

2024

Cytomegalovirus retinitis (CMVR) is a significant cause of blindness in patients with advanced acquired immunodeficiency syndrome (AIDS). There are no established guidelines for its treatment, resulting in varied antiviral approaches....

The impact of undernutrition and anemia on HIV-related mortality among children on ART in sub-Saharan Africa: A systematic review and meta-analysis

2024

BACKGROUND: Although there have been significant advancements in providing HIV-infected children with access to antiretroviral therapy (ART), the mortality rates have remained unacceptably high. Inadequate nutrient intake or absorption is...

Skin cancer in patients who are co-infected with HIV/ HBV or HIV/HCV: A systematic review

2024

Skin cancer, the most common cancer in the United States, has been well-described in the literature to be associated with environmental factors including ultraviolet (UV) radiation. However, the effect of...

Gut microbiome alteration in HIV/AIDS and the role of antiretroviral therapy—A scoping review

2024

(1) Background: The gut microbiota plays a crucial role in chronic immune activation associated with human immunodeficiency virus (HIV) infection, acquired immune deficiency syndrome (AIDS) pathogenesis, non-AIDS-related comorbidities, and mortality...

“It’s like it’s the old boys club”—The age-related experiences of diverse older women living with HIV: A scoping review and consultative exercise

2024

Objectives HIV is often under-recognized in older individuals, particularly women, despite a significant number of new cases being diagnosed in those aged >50 years. This review aimed to understand the age-related...

Complications due to HIV in patients undergoing total joint arthroplasty: A systematic review and meta-analysis

2025

Background: HIV infection in patients undergoing Total joint arthroplasty (TJA) results in adverse postoperative outcomes. However, there are uncertain data regarding the extent of involvement of HIV in TJA and the...

Patient reported experiences in older adults living with

2025

Effective antiretroviral therapy has extended the life expectancy of people living with HIV and in Western countries, with 50% of individuals in Western countries now aged 50 or older. The...

HIV, the gut microbiome and clinical outcomes, a systematic review

2024

BACKGROUND: Effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH). However, this population is now experiencing accelerated age-related comorbidities, contributed to by chronic immune activation...

Developing an HIV-specific falls risk prediction model with a novel clinical index: A systematic review and meta-analysis method

2024

Background Falls are a common problem experienced by people living with HIV yet predictive models specific to this population remain underdeveloped. We aimed to identify, assess and stratify the predictive...

Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis

2025

This meta-analysis aimed to quantify the latest cardiovascular disease (CVD) incidence rate and assess the impact of risk factors among people living with HIV (PLWH). We searched PubMed, Embase, Web...

Food consumption and cardiovascular risk in children and adolescents living with HIV: A systematic review

2025

The aim of this systematic review was to summarize the dietary intake of children and adolescents living with HIV and its association with cardiovascular risk factors. PubMed/MEDLINE, Scopus, Web of...

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