Category Archives: Co-morbidities

Etiology of spinal cord injuries in Sub-Saharan Africa

2011

STUDY DESIGN: Review. OBJECTIVES: The aim is to highlight the epidemiology of spinal cord injuries (SCIs) in Sub-Saharan Africa in order to improve prevention strategies. SETTING: University Hospitals Leuven, Belgium....

Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: A systematic review and meta-analysis

2010

In patients with HIV-1 infection who are starting combination antiretroviral therapy (ART), the incidence of immune reconstitution inflammatory syndrome (IRIS) is not well defined. We did a meta-analysis to establish...

Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials

2008

OBJECTIVES: We performed a meta-analysis to assess the efficacy and safety of switching from protease inhibitor (PI)- to nevirapine (NVP)-based regimens in HIV-infected patients in whom virological suppression had been...

Second-line salvage treatment of AIDS-associated Pneumocystis jirovecii pneumonia: A case series and systematic review

2008

Background: Limited clinical data exist to guide the choice of second-line salvage treatment for AIDS-associated Pneumocystis jirovecii pneumonia (PCP). Methods: We did a systematic search of MEDLINE for all randomized...

Treatment for leiomyosarcoma and leiomyoma in children with HIV infection

2010

BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...

Interventions for anal canal intraepithelial neoplasia

2012

Background: Anal canal intraepithelial neoplasia (AIN) is a pre-malignant condition of the anal canal transitional epithelium that is associated with human papillomavirus (HPV) infection. The incidence and prevalence of AIN...

Cardiovascular manifestations of HIV infection in children

2014

BACKGROUND: HIV infection in children is now considered as a chronic condition, in which various non-infectious complications may occur, including those affecting the developing cardiovascular system. As children are expected...

Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: A meta-analysis of six prospective, randomized, comparative studies

2004

Background: Hematologic changes that occur with HIV infection and antiretroviral therapy may impact the quality of life of patients and have been associated with morbidity and mortality. The management of...

Human T-lymphotropic virus/HIV co-infection: A clinical review

2014

PURPOSE OF REVIEW: Human T-lymphotropic virus (HTLV)/HIV co-infections are often undiagnosed, with important clinical implications. The literature is relatively sparse with key observations derived in the pre-highly-active antiretroviral therapy era....

Protease inhibitors and avascular necrosis: A systematic review and meta-analysis

2014

Avascular necrosis (AVN) is a pathological process associated with many medical conditions, including human immunodeficiency virus (HIV) infection. Whether or not the use of protease inhibitors (PIs) confers additional risk...

The motor evoked potential in AIDS and HAM/TSP: State of the evidence

2009

OBJECTIVE: We aimed to better understand the involvement of the corticospinal tract, assessed by non-invasive transcranial stimulation, in order to determine the actual involvement of the motor system in patients...

Isoniazid prophylaxis for tuberculosis in HIV infection: A meta-analysis of randomized controlled trials

1999

OBJECTIVES: To evaluate the efficacy of isoniazid for the prevention of tuberculosis in tuberculin skin test-positive and negative individuals with HIV infection. DESIGN: Meta-analysis of randomized controlled trials. SETTING: Seven...

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