Category Archives: Epidemiology

The mental health of adults living with HIV in sub-Saharan Africa: Interventions along the HIV care continuum—A systematic review

2026

Although the relationship between HIV and mental health is well-established, limited research has focused on the available interventions for adults living with HIV (ALWH), particularly those in sub-Saharan Africa (SSA)...

Prevalence and risk factors for oropharyngeal, esophageal, and oral candidiasis in HIV-positive individuals: A systematic review and meta-analysis

2026

Background: Oral, oropharyngeal, and esophageal candidiasis are common forms of mucosal candidiasis (MC) in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Despite differences in infection sites, oral, oropharyngeal, and...

Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis

2026

INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...

The global re-emergence of syphilis and antimicrobial resistance among men who have sex with men (MSM), people living with HIV (PLWH), and newborns: A narrative review

2026

Syphilis incidence continues to rise substantially among men who have sex with men (MSM), people living with HIV (PLWH), newborns, and women of reproductive age, despite preventive measures and available...

Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature

2026

Background The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...

Prevalence and risk factors for cytomegalovirus retinitis among people living with HIV in sub-Saharan Africa in the antiretroviral therapy era: A systematic review and meta-analysis

2026

Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...

Prevalence of left ventricular systolic dysfunction in HIV-infected children from sub-Saharan Africa: A systematic review and meta-analysis

2026

Background Left ventricular systolic dysfunction (LVSD) is an emerging non-communicable complication among children living with Human Immunodeficiency Virus (HIV), particularly in Sub-Saharan Africa, where paediatric HIV burden remains high. However,...

Exclusive breastfeeding and associated factors among HIV-infected mothers in sub-Saharan African countries: A systematic review and meta-analysis

2026

Introduction The World Health Organization recommends exclusive breastfeeding for the first six months, along with maternal antiretroviral treatment, to reduce the risk of HIV transmission to infants and promote their...

Assessing the state of published HIV research concerning sexual minority women: A global English language scoping review

2026

PURPOSE: We conducted a scoping review to map peer-reviewed literature on HIV research concerning sexual minority women (SMW). METHODS: Following guidance from Arksey and O’Malley’s framework and the Preferred Reporting...

Prevalence of hypertension, diabetes, obesity, and high cholesterol among older people living with HIV: A systematic review and meta-analysis

2026

INTRODUCTION: Metabolic comorbidities are significant health challenges for older people living with HIV (PLHIV). This systematic review and meta-analysis aimed to synthesize existing evidence and provide the pooled prevalence of...

Prevalence, genetic diversity, and risk factors of cryptosporidium spp. in HIV/AIDS patients: An updated systematic review and meta-analysis (2017–2025)

2026

Background Cryptosporidium spp. is a major opportunistic pathogens in HIV/AIDS patients, contributing substantially to morbidity and mortality worldwide. Despite advances in HIV/AIDS management, the global burden, genetic diversity, and risk factors...

The role of subtyping methodologies in HIV surveillance and vaccine development: A systematic review and meta-analysis

2026

BACKGROUND: HIV genetic diversity has increased over time, with recombinant forms becoming more prevalent and complicating subtype classification and surveillance, particularly in low-and-middle income countries (LMICs). Accurate subtyping is critical...

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