Category Archives: Epidemiology
People who living with HIV/AIDS also have a high prevalence of anxiety disorders: A systematic review and meta-analysis
BACKGROUND: An estimated 301 million people worldwide suffer from anxiety disorders. People living with HIV/AIDS (PLWHA) are particularly prone to anxiety disorders that could interfere with the important developmental process...
The level of antiretroviral therapy (ART) adherence among orphan children and adolescents living with HIV/AIDS: A systematic review and meta-analysis
Background Many children and adolescents living with HIV have ended up as orphans. Due to HIV taking away their parents leaves them deprived of their most important social network and...
HIV pre-exposure prophylaxis uptake among high-risk population in sub-Saharan Africa: A systematic review and meta-analysis
Globally, 38.4 million people are affected by the human immunodeficiency virus (HIV) pandemic, and more than 2.5 million new HIV infections occur yearly. HIV pre-exposure prophylaxis (PrEP) has been widely...
Systematic review: Strategies for improving HIV testing and detection rates in European hospitals
Undiagnosed HIV infection is a prominent clinical issue throughout Europe that requires the continuous attention of all healthcare professionals and policymakers to prevent missed testing opportunities and late diagnosis. This...
Same-day ART initiation, loss to follow-up and viral load suppression among people living with HIV in low- and middle-income countries: Systematic review and meta-analysis
INTRODUCTION: in 2015, the World Health Organization recommended early antiretroviral therapy (ART) initiation after HIV diagnosis. Mixed results on the effect of same-day ART initiation (SDI) over non-same-day ART initiation...
Association of vitamin D with HIV infected individuals, TB infected individuals, and HIV-TB co-infected individuals: A systematic review and meta-analysis
Background Vitamin D deficiency (VDD) is a worldwide disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active...
The effect of HIV and mpox co-infection on clinical outcomes: Systematic review and meta-analysis
Introduction: Co-infection with HIV and mpox is a significant issue for public health because of the potential combined impact on clinical outcomes. However, the existing literature lacks a comprehensive synthesis of...
Interventions, barriers, and facilitators to address the sexual problems of gay, bisexual and other men who have sex with men living with HIV: A rapid scoping review
Sexual problems are common among gay, bisexual, and other men who have sex with men (GBM) after diagnosis with HIV. However, these are often overlooked in care and research, where...
Disparities in COVID-19 mortality amongst the immunosuppressed: A systematic review and meta-analysis for enhanced disease surveillance
Background Effective disease surveillance, including that for COVID-19, is compromised without a standardised method for categorising the immunosuppressed as a clinical risk group. Methods We conducted a systematic review and...
High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: A systemic review and meta-analysis
The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The current systematic review...
Impact of harm minimization interventions on reducing blood-borne infection transmission and some injecting behaviors among people who inject drugs: An overview and evidence gap mapping
Background This study aimed to synthetize the evidence on the effectiveness of harm minimization interventions on reducing blood-borne infection transmission and injecting behaviors among people who inject drugs (PWID) through...