Category Archives: Epidemiology

Does genetic diversity of HIV-1 non-B subtypes differentially impact disease progression in treatment-naive HIV-1-infected individuals? A systematic review of evidence: 1996–2010

2012

With 88% of HIV-1-infected individuals living in areas of high prevalence of non-B subtypes and with expanded global access to antiretroviral treatment (ART), studying disease progression amongst non-B subtypes gains...

Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: A systematic review and meta-analysis

2012

BACKGROUND: Men who have sex with men (MSM) are at greatly increased risk of human papillomavirus (HPV)-associated anal cancer. Screening for the presumed cancer precursor, high-grade anal intraepithelial neoplasia (AIN),...

The impact of HIV treatment as prevention in the presence of other prevention strategies: Lessons learned from a review of mathematical models set in resource-rich countries

2013

OBJECTIVE: We aimed to assess the potential prevention benefits of HIV treatment as prevention (TasP) in resource-rich countries and examine the potential interactions between TasP and other prevention strategies by...

Epidemiology of HIV infection in the Middle East and North Africa

2010

OBJECTIVE: The Middle East and North Africa (MENA) region continues to be perceived as a region with very limited HIV epidemiological data, raising many controversies about the status of the...

Uncovering the epidemic of HIV among men who have sex with men in Central Asia

2013

BACKGROUND: Research among people who inject drugs (PWID) in Central Asia has described same sex behavior among male PWID and may be associated with HIV and other infections. Little is...

The Indian pediatric HIV epidemic: A systematic review

2008

Despite an estimated 70,000 Indian children living with HIV infection, little is known about India’s pediatric HIV epidemic. Generalizations about epidemiology, natural history, and treatment outcomes from other resource-limited settings...

The utility of voluntary counselling and testing data as a source of information on HIV prevalence: A systematic review

2010

We explored the utility of routine HIV testing data from clinical services for estimating HIV prevalence. A systematic review identified 28 eligible publications, covering concentrated epidemics (16 of 28) and...

AIDS in Latin America: Assessing the current status of the epidemic and the ongoing response

2008

Background: This article provides a summary of the current status of the HIV/AIDS epidemic in Latin America, as well as an outline of the diverse responses to it. Methods: A...

Iron supplementation for reducing morbidity and mortality in children with HIV

2009

BACKGROUND: The most prevalent haematologic disturbance associated with HIV in children (apart from CD4 lymphocytopenia) is anaemia. Anaemia associated with HIV arises from multiple mechanisms, including the direct inhibitory effect...

Mathematical models for the study of HIV spread and control amongst men who have sex with men

2011

For a quarter of century, mathematical models have been used to study the spread and control of HIV amongst men who have sex with men (MSM). We searched MEDLINE and...

A decline in HIV and syphilis epidemics in Chinese female sex workers (2000-2011): A systematic review and meta-analysis

2013

BACKGROUND: Female sex workers (FSWs) play an important role in transmitting HIV and syphilis from high-risk groups to the general population. However, the trends in HIV and syphilis epidemics in...

Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection

2011

Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...

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