Category Archives: Epidemiology
A decline in HIV and syphilis epidemics in Chinese female sex workers (2000-2011): A systematic review and meta-analysis
BACKGROUND: Female sex workers (FSWs) play an important role in transmitting HIV and syphilis from high-risk groups to the general population. However, the trends in HIV and syphilis epidemics in...
Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection
Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...
HIV infection and sexual risk behaviour among youth who have experienced orphanhood: Systematic review and meta-analysis
BACKGROUND: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and...
Intravaginal practices, bacterial vaginosis, and HIV infection in women: Individual participant data meta-analysis
BACKGROUND: Identifying modifiable factors that increase women’s vulnerability to HIV is a critical step in developing effective female-initiated prevention interventions. The primary objective of this study was to pool individual...
HIV prevalence in China: Integration of surveillance data and a systematic review
BACKGROUND: Asian HIV epidemics are concentrated among particular behavioural groups, but large variations exist in epidemic types, timing, and geographical spread between countries and within countries, especially in China. We...
Burden of HIV-related CMV retinitis in resource-limited settings: A systematic review
Background. Cytomegalovirus (CMV) is a late stage opportunistic infection in people living with HIV/AIDS. Lack of ophthalmological diagnostic skills or convenient CMV treatment and increasing access to antiretroviral therapy, have...
A systematic review on the meaning of the concept ‘AIDS Orphan’: Confusion over definitions and implications for care
Global publications on the international AIDS epidemic report on the existence of an ever-increasing number of orphans and vulnerable children. It has been suggested that by the end of this...
Accuracy of serological assays for detection of recent infection with HIV and estimation of population incidence: A systematic review
We systematically reviewed the accuracy of serological tests for recent infections with HIV that have become widely used for measuring population patterns incidence of HIV. Across 13 different assays, sensitivity...
