Category Archives: Epidemiology

Prevalence and factors influencing HIV testing behavior in adolescents and young adults: A systematic review and meta-analysis

2025

Objective To systematically evaluate the prevalence and influencing factors of human immunodeficiency virus (HIV) testing among adolescents and young adults (10–25 years old), providing a reference for optimizing testing strategies and...

Deep vein thrombosis in adults with HIV: A systematic review and meta-analysis of prevalence and risk factors

2025

Deep vein thrombosis (DVT) is a preventable yet serious complication among people living with human immunodeficiency virus (PLWH), attributed to hypercoagulability, low CD4+ counts, and antiretroviral therapy. Despite the high...

Prevalence and factors associated with HIV viral rebound in individuals on ART: A systematic review study

2025

BACKGROUND: Viral rebound (VR), the resurgence of detectable human immunodeficiency virus (HIV) viral loads (> 50 copies/mL) after suppression, remains a challenge for individuals on antiretroviral therapy (ART) in South...

Advanced stage disease progression and mortality rate before and after the implementation of the Universal Test and Treat strategy (UTT) for HIV patients in Ethiopia: A systematic review and meta-analysis

2025

BACKGROUND: The universal test and treat (UTT) program, is a strategy for eliminating HIV and, it involves screening all populations at risk for HIV infection, initiating early treatment for those...

Prevalence of opportunistic bacterial infections (tuberculosis and pneumonia) among people with HIV in Ethiopia: Systematic review and meta-analysis

2025

BACKGROUND: Individuals with weakened immune systems, such as those living with Human Immunodeficiency Virus (HIV), are more vulnerable to opportunistic bacterial infections, which include tuberculosis and pneumonia. This systematic review...

Prevalence and resistance patterns of Mycoplasma genitalium infection in people with HIV: A systematic review and meta-analysis

2025

Objectives: This study aimed to estimate the prevalence of M. genitalium infection and understand the patterns of resistance associated mutations (resistance hereafter) in people with HIV (PWH). Methods: We searched PubMed-MEDLINE, Embase...

Effectiveness of tuberculosis preventive treatment on disease incidence among people living with HIV/AIDS: A systematic review and meta-analysis

2025

Background Clinical trials have shown the protective efficacy of tuberculosis preventive treatment (TPT) for averting disease and death from tuberculosis among people living with HIV/AIDS (PLHIV). TPT has been recommended...

State of HIV research in Venezuela: A systematic review

2025

BACKGROUND: Venezuela’s recent economic and political instability has severely compromised its healthcare infrastructure, impacting the management of infectious diseases, including human immunodeficiency virus (HIV). This disruption hinders progress towards the...

HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: A systematic review and meta-regression analysis

2025

Background: Past cohort studies have examined mortality among children and young adolescents (aged 0–14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these...

Probability of vertical HIV transmission: A systematic review and meta-regression

2025

Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...

A global meta-analysis of gonorrhoea and chlamydia prevalence among men who have sex with men from 2000 to 2022

2025

IntroductionWe conducted a global systematic review and meta-analysis of gonorrhoea and chlamydia among men who have sex with men (MSM) from 2000 to 2022.MethodsWe searched four databases to identify studies...

Sensory neuropathy and associated factors among patients living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Introduction Despite high prevalence of sensory neuropathy among individuals living with HIV, there is no comprehensive information regarding variables that determine sensory neuropathy onset among the patients who attended health...

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