Category Archives: Epidemiology
Screening performance of C-reactive protein for active pulmonary tuberculosis in HIV-positive patients: A systematic review with a meta-analysis
BACKGROUND: Tuberculosis (TB) is the leading infectious cause of mortality worldwide. In the last years, resistant strains of the etiological agent, Mycobacterium tuberculosis, have emerged, thus demanding more triage tests...
Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review
OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries...
Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis
Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...
Adherence to option B+ and its association with disclosure status and counseling among HIV-positive pregnant and lactating women in Ethiopia: Systematic review and meta-analysis
Objectives: This systematic review and meta-analysis aimed to assess the pooled estimate of option B+ level of adherence and its association with disclosure status and counseling among pregnant and lactation women...
Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A systematic review and meta-analysis
BACKGROUND: Cryptococcal meningitis (CM) is a leading cause of adult meningitis in countries with a high burden of HIV. It has remained a significant cause of morbidity and mortality in...
Comparing the effects of oral HIV self-testing with those of standard HIV testing for men who have sex with men (MSM): A systematic review and meta-analysis
The WHO recommends HIV self-testing (HIVST) as an innovative strategy and an additional testing approach to attain UNAIDS targets to end HIV by 2030. HIVST is a process whereby a...
HIV prevalence ratio of international migrants compared to their native-born counterparts: A systematic review and meta-analysis
Background: People on the move, including international migrants, may face health inequities that expose them to a higher risk for HIV than native-born populations. We conducted a systematic review to calculate...
Immunogenicity and safety of COVID-19 vaccines among people living with HIV: A systematic review and meta-analysis
BACKGROUND: The immunogenicity and safety of COVID-19 vaccines among people living with human immunodeficiency virus (PLWH) are unclear. We aimed to evaluate the immunogenicity and safety of COVID-19 vaccines among...
Men who have sex with men is the high-risk drug resistance population: A meta-analysis of HIV-1 drug resistance profiles and trends in China
WHAT IS KNOWN AND OBJECTIVE: Except for the transmitted drug resistance (TDR)’s standard sampling and monitoring protocol, China’s HIV-1 pretreatment drug resistance (PDR) and acquired drug resistance (ADR) results vary...
The global burden of cognitive impairment in people living with HIV: A systematic review and meta-analysis
Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for...
Malaria prevalence in HIV-positive children, pregnant women, and adults: A systematic review and meta-analysis
Background: Malaria in human immunodeficiency virus (HIV)-positive patients is an ever-increasing global burden for human health. The present meta-analysis summarizes published literature on the prevalence of malaria infection in HIV-positive children,...