Category Archives: Epidemiology

Global, regional, and national prevalence of HIV-1 drug resistance in treatment-naive and treatment-experienced children and adolescents: A systematic review and meta-analysis

2024

Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 drug resistance (HIVDR) in treatment-naive and...

Adverse perinatal outcomes associated with different classes of antiretroviral drugs in pregnant women living with HIV: A systematic review and meta-analysis

2024

OBJECTIVE: Women living with HIV (WLHIV) are at increased risk of adverse perinatal outcomes compared to HIV-negative women, despite antiretroviral therapy (ART). There is evidence that the risk of adverse...

Exploring optimal HAART adherence rates in Ethiopian adults: A systematic review and meta-analysis

2024

BACKGROUND: Optimal medication adherence is vital for the successful implementation of highly active antiretroviral therapy (HAART) in managing HIV infection. Global efforts aim to minimize the burden of antimicrobial resistance...

Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in Southeast Asia: A systematic review and meta-analysis

2024

The dual burden of human immunodeficiency virus (HIV) and tuberculosis (TB) impacts people living with HIV (PLHIV) coinfected with TB. Although some primary studies have been reported on the burden...

A systematic review of factors associated with COVID-19 vaccine uptake, hesitancy, and acceptability among adults with HIV: Implications for integrating COVID-19 immunization into HIV care

2024

The COVID-19 virus, once a public health emergency, is now endemic. Immunization remains an important measure for mitigating high levels of disease, morbidity, and mortality related to COVID-19 infection. People...

Maternal inflammatory and microbial drivers of low birthweight in low- and middle-income countries

2024

BACKGROUND: Low birthweight (LBW) is when an infant is born too soon or too small, and it affects one in seven infants in low- and middle-income countries. LBW has a...

Prevalence of Giardia duodenalis among African children: A systematic review and meta-analysis

2024

BACKGROUND: Giardia duodenalis (G. duodenalis) is one of the major causes of diarrhea among children. We performed a systematic review and meta-analysis to assess the prevalence of G. duodenalis and...

Magnitude of consistent condom use and associated factors among people living with HIV/AIDS in Ethiopia: Implication for reducing infections and re-infection. A systematic review and meta-analysis

2024

BACKGROUND: The human immune virus or acquired immune deficiency syndrome, is a major threat to the health of millions of people worldwide. In Ethiopia, there were more than a million...

The impact of HIV upon the PCI results: A systematic review and meta-analysis

2024

The aim of this systematic review and meta-analysis was to comprehensively evaluate the latest evidences and summarise the impact of HIV on PCI outcomes. A PRISMA guided literature search was...

Prevalence of co-trimoxazole resistance among HIV-infected individuals in Ethiopia: A systematic review and meta-analysis

2024

Background Co-trimoxazole is used as a prophylaxis for human immunodeficiency virus (HIV) patients to prevent opportunistic infections. Its widespread use results in the emergence of co-trimoxazole resistance, which is a...

Effectiveness of MenB-4C vaccine against gonorrhea: A systematic review and meta-analysis

2024

Introduction: There is no licensed vaccine against gonorrhea but Neisseria meningitidis serogroup B outer membrane vesicle-based vaccines, like MenB-4C, may offer cross-protection against gonorrhea. This systematic review and meta-analysis synthesized...

Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa: A systematic review and meta-analysis

2024

We perfWe performed a systematic review and meta-analysis of hypertension in people living with human immunodeficiency virus (HIV) in sub-Saharan Africa (SSA). We searched the PubMed, Google Scholar, African Index...

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