Category Archives: Epidemiology

Prevalence of HHV-6 detection among people living with HIV: A systematic review and meta-analysis

2025

Human herpesvirus 6 (HHV-6) is a ubiquitous virus with significant implications for immunocompromised individuals, particularly people living with HIV (PLWH). This study aimed to estimate the prevalence of HHV-6 detection...

Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review

2025

Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...

Global, regional, and national estimates of hepatitis C virus (HCV) infection incidence among people who inject drugs and number of new annual HCV infections attributable to injecting drug use: A multi-stage analysis

2025

Background: Measuring progress towards the WHO 2030 target for hepatitis C virus (HCV) elimination among people who inject drugs (PWID)-an incidence of two or fewer infections per 100 person-years-has been challenging...

Kidney dysfunction and associated factors among adults living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Background Kidney dysfunction among adults living with Human Immuno-Deficiency Virus (HIV) increases the risk of drug-related side effects, acute kidney injury, hospitalization, and progression to end-stage kidney disease. In developing...

Challenges in elucidating HIV-1 genetic diversity in the Middle East and North Africa: A review based on a systematic search

2025

The extensive genetic diversity of HIV-1 represents a major challenge to public health interventions, treatment, and successful vaccine design. This challenge is particularly pronounced in the Middle East and North...

Self-reported sleep disturbances among people living with HIV in China: A systematic review and meta-analysis

2025

Objective: People living with HIV (PLWH) commonly face a range of health issues, among which sleep disturbances are common and are related to adverse health outcomes. This review aims to assess...

Prevalence and burden of HBV-HIV co-morbidity: A global systematic review and meta-analysis

2025

Introduction Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). Because of the shared modes of transmission, co-infections of HBV are common among people living...

HIV prevention interventions and research in the philippines for high-risk populations: Proposals from a scoping review of contributing cactors

2025

Despite a global decrease in HIV cases and efforts to reduce HIV incidence in the country, the Philippines has an increasing HIV incidence rate, which is the highest in the...

The global prevalence and impact of steatotic liver disease and viral infections: A systematic review and meta-analysis

2025

Background: Steatotic liver disease (SLD) affects ~30% of adults worldwide. The global population is continuously threatened by epidemic and endemic viral diseases. This study aims to thoroughly examine the interaction...

The prevalence of nonalcoholic fatty liver disease in people living with HIV: A systematic review and meta-analysis

2025

Background: Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD...

Climate change and extreme weather events and linkages with HIV outcomes: Recent advances and ways forward

2025

PURPOSE OF REVIEW: Discuss the recent evidence on climate change and related extreme weather events (EWE) and linkages with HIV prevention and care outcomes. RECENT FINDINGS: We identified 22 studies...

Growth and body composition of adolescents and young adults with perinatal HIV infection: A systematic review and meta-analysis

2025

Introduction: Approximately 1.3 million pregnancies are exposed to HIV perinatally each year, with transmission rates ranging from 4 to 21%, despite 85% antiretroviral therapy (ART) coverage among pregnant women. While ART...

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