Category Archives: Epidemiology
Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis
The development of effective combined anti-retroviral therapy (cART) led to a significant reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) infection. However, recent studies indicate...
Long-acting reversible contraception, condom use, and sexually transmitted infections: A systematic review and meta-analysis
Introduction Given mixed findings regarding the relationship between long-acting reversible contraception and condom use, this systematic review and meta-analysis synthesizes studies comparing sexually transmitted infection‒related outcomes between users of long-acting...
Global prevalence and associated risk factors of diarrheagenic Giardia duodenalis in HIV/AIDS patients: A systematic review and meta-analysis
Giardia duodenalis is one of the leading causes of diarrhea, mostly in underdeveloped nations of Africa and Asia. The present review provides insights into the prevalence, odds ratios (ORs) and...
Integrative review on the incidence of HIV infection and its socio-spatial determinants
OBJECTIVES: to identify the socio-spatial determinants associated with the incidence of infection by the human immunodeficiency virus (HIV) described in national and international literature. METHODS: integrative literature review that included...
Availability and quality of surveillance and survey data on HIV prevalence among sex workers, men who have sex with men, people who inject drugs, and transgender women in low- and middle-income countries: Review of available data (2001–2017)
BACKGROUND: In 2019, 62% of new HIV infections occurred among key populations (KPs) and their sexual partners. The World Health Organization (WHO) recommends implementation of bio-behavioral surveys every 2–3 years...
Under-reporting of known HIV-positive status among people living with HIV: A systematic review and meta-analysis
Monitoring progress towards the UNAIDS ‘first 90’ target requires accurate estimates of levels of diagnosis among people living with HIV (PLHIV), which is often estimated using self-report. We conducted a...
Prevalence of HIV and HCV among injecting drug users in three selected WHO-EMRO countries: A meta-analysis
BACKGROUND: HIV and Hepatitis C Virus (HCV) infections are responsible for a significant burden of mortality and morbidity, particularly in developing countries. This study sought to determine the prevalence of...
The value of assessing self-reported and biological indicators of outcomes in evaluating HIV programs
PURPOSE OF REVIEW: In this manuscript, we present recent findings concerning concordance and discrepancy between biological measures and self-reports of these three outcomes of HIV programs: HIV status, adherence to...
The HIV care cascade in sub-Saharan Africa: Systematic review of published criteria and definitions
INTRODUCTION: The HIV care cascade examines the attrition of people living with HIV from diagnosis to the use of antiretroviral therapy (ART) and suppression of viral replication. We reviewed the...