Category Archives: Epidemiology
Structural determinants of HIV/STI prevalence, HIV/STI/sexual and reproductive health access, and condom use among immigrant sex workers globally
OBJECTIVE: Given stark health inequities among precarious and criminalized workers, we aimed to apply a structural determinants framework to systematically review evidence on HIV/sexually transmitted infection (STI) prevalence, access to...
Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: A systematic review
BACKGROUND: As infectious diseases approach global elimination targets, spatial targeting is increasingly important to identify community hotspots of transmission and effectively target interventions. We aimed to synthesise relevant evidence to...
Global estimate of phenotypic and genotypic ganciclovir resistance in cytomegalovirus infections among HIV and organ transplant patients; A systematic review and meta-analysis
Human cytomegalovirus (CMV), an opportunistic pathogen belonging to Herpesviridae family, is considered as one of the major causes of morbidity and mortality among wide variety of patients, particularly in transplant...
Prevalence and burden of HBV co-infection among people living with HIV: A global systematic review and meta-analysis
Globally, in 2017 35 million people were living with HIV (PLHIV) and 257 million had chronic HBV infection (HBsAg positive). The extent of HIV-HBsAg co-infection is unknown. We undertook a...
Overweight and obesity among adult HIV infected peoples receiving ART in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Over-nutrition and diet-linked non-communicable morbidities are showing increasing trend overtime. Even if there are different factors that affect the change in BMI other than ART, several authors have reported...
Global burden of hepatitis B Infection in people living with human immunodeficiency virus: A systematic review and meta-analysis
Background: This meta-analysis was conducted to estimate the global burden of hepatitis B virus (HBV) infection in people living with human immunodeficiency virus (PLWH). Methods: We searched multiple databases for studies published between...
The prevalence of laboratory-confirmed Pneumocystis jirovecii in HIV-infected adults in Africa: A systematic review and meta-analysis
BACKGROUND: The epidemiology of Pneumocystis jirovecii, known to colonize the respiratory tract and cause a life-threatening HIV-associated pneumonia (PCP), is poorly described in Africa. We conducted a systematic review to...
Recurrent TB: a systematic review and meta-analysis of the incidence rates and the proportions of relapses and reinfections
Background: A recurrent tuberculosis (TB) episode results from exogenous reinfection or relapse after cure. The use of genotyping allows the distinction between both. Methods: We did a systematic review and meta-analysis, using four...
Incidence and predictors of tuberculosis among HIV patients after initiation of antiretroviral treatment in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Tuberculosis is the oldest infectious disease and it is still the leading cause of morbidity and mortality worldwide. Even though several primary studies have been conducted on the incidence...