Category Archives: Epidemiology

Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: A global systematic review and meta-analysis

2022

Background: Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its clinical and public health benefits. This study synthesises evidence regarding discontinuation, adherence, and reinitiation of PrEP among geographically diverse PrEP...

Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: A network meta-analysis

2022

Background: Global antiretroviral therapy has entered a new era. Integrase strand transfer inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) treatment. Because INSTI has high antiviral efficacy,...

Effects of interleukin-10 -1082G/A and -592C/A gene polymorphisms on the risk of human immunodeficiency virus-1 infection: An updated meta-analysis

2022

This paper has aimed to review the available evidence on the association between Interleukin (IL) -10 -1082G/A, -592C/A gene polymorphisms and the risk of human immunodeficiency virus-1(HIV-1) infection. The data...

Magnitude and associated factors of urinary tract infections among adults living with HIV in Ethiopia—Systematic review and meta-analysis

2022

BACKGROUND: Urinary tract infection is a major public health problem in developing countries among immunocompromized populations where there are limited health-care services. People living with human immunodeficiency virus (HIV) are...

The impact of genital ulcers on HIV transmission has been underestimated—A critical review

2022

In the early 1990s, several observational studies determined that genital ulcer disease (GUD), in either the index or the exposed person, facilitates HIV transmission. Several meta-analyses have since presented associated...

The association between methamphetamine use and number of sexual partners in men who have sex with men: A systematic review and meta-analysis

2022

BACKGROUND: Methamphetamine use in men who have sex with men population is significantly higher than that in the general population. Meth use can cause high-risk sexual behaviors, such as having...

Tuberculosis screening among HIV-positive inpatients: A systematic review and individual participant data meta-analysis

2022

Background: Since 2011, WHO has recommended that HIV-positive inpatients be routinely screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened positive, receive a molecular WHO-recommended rapid diagnostic test...

Prevalence and associated factors of treatment failure among children on ART in Ethiopia: A systematic review and meta-analysis

2022

BACKGROUND: As the use of antiretroviral therapy (ART) increases, the issue of treatment failure is still a global challenge, particularly in a resource limited settings including Ethiopia. The results of...

Outcomes of people living with HIV after hospital discharge: A systematic review and meta-analysis

2022

Background: The identification and appropriate management of people with advanced HIV disease is a key component in the HIV response. People with HIV who are hospitalised are at a higher risk...

Integrating care for diabetes and hypertension with HIV care in sub-Saharan Africa: A scoping review

2022

INTRODUCTION: Although HIV continues to have a high prevalence among adults in sub-Saharan Africa (SSA), the burden of noncommunicable diseases (NCD) such as diabetes and hypertension is increasing rapidly. There...

Prevalence of human papillomavirus infection in Brazilian women living with HIV: A systematic review and meta-analysis

2022

Objective: We systematically investigated the prevalence of HPV, high-risk HPV and its genotypes in women living with human immunodeficiency virus (WLHIV) in Brazil. Methods: A systematic search was performed up to 15...

Condomless sex with partners and clients among female sex workers in Iran: A systematic review and meta-analysis

2022

Condomless sex is the most proximal risk for HIV acquisition among female sex workers (FSWs). We performed a systematic review and meta-analysis to summarize the evidence for the prevalence of...

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