Category Archives: Epidemiology
Oral mycobiome identification in atopic dermatitis, leukemia, and HIV patients — A systematic review
INTRODUCTION: Oral mycobiome profiling is important to understand host-pathogen interactions that occur in various diseases. Invasive fungal infections are particularly relevant for patients who have received chemotherapy and for those...
Magnitude of underweight, wasting and stunting among HIV positive children in East Africa: A systematic review and meta-analysis
BACKGROUND: Malnutrition on the background of HIV (Human Immunodeficiency Virus) infection is a complex medical condition that carries significant morbidity and mortality for affected children, with greater mortality from SAM...
Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence
BACKGROUND: The triple burden of COVID-19, tuberculosis and human immunodeficiency virus is one of the major global health challenges of the twenty-first century. In high burden HIV/TB countries, the spread...
Hepatitis E seroprevalence and viremia rate in immunocompromised patients: A systematic review and meta-analysis
BACKGROUND AND AIMS: Hepatitis E is an infectious disease of the liver caused by the hepatitis E virus (HEV). Immunocompromised patients present a particular risk group, as chronification of hepatitis...
Risk of failure in dual therapy versus triple therapy in naive HIV-patients: A systematic review and meta-analysis
BACKGROUND: Several attempts have been made to test different drug-sparing strategies to reduce the drug-burden and drug-related toxicities. OBJECTIVE: The objective of this meta-analysis was to evaluate the relative risk...
The prevalence of latent and acute toxoplasmosis in HIV-infected pregnant women: A systematic review and meta-analysis
OBJECTIVE: HIV in pregnancy is not only important for mother-to-child HIV transmission, but also it assumes additional importance because HIV increases susceptibility to opportunistic infections, leading to increased morbidity and...
Prevalence and type distribution of human papillomavirus recovered from the uterine cervix of Nigerian women: A systematic review and meta-analysis
BACKGROUND: Infection with an oncogenic type of human papillomavirus is a prerequisite for the development of precancerous cervical lesions and its subsequent progression to cervical cancer. With an alarming increase...
Prevalence of vertical HIV infection and its risk factors among HIV exposed infants in East Africa: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) is one of the most important global health problems. More than one and half million of children are living with HIV in the world, and...
A systematic review and meta-analysis to assess the association between urogenital schistosomiasis and HIV/AIDS infection
BACKGROUND: Urogenital schistosomiasis and HIV/AIDS infections are widespread in sub-Saharan Africa (SSA) leading to substantial morbidity and mortality. The co-occurrence of both diseases has led to the possible hypothesis that...
Global burden of hypertension among people living with HIV in the era of increased life expectancy: A systematic review and meta-analysis
BACKGROUND: Although HIV infection and antiretroviral therapy (ART) increase the risk for hypertension in people living with HIV (PLHIV), the global and regional burden of hypertension in PLHIV is not...