Category Archives: Epidemiology
Clostridium difficile in immunocompromised hosts: A review of epidemiology, risk factors, treatment, and prevention
Clostridium difficile is a significant pathogen in healthcare today, impacting both hospitalized and community-based patients. Immunocompromised patients experience a high incidence of C. difficile infection, ranging from 6% to 33%...
Impact of male circumcision on risk of HIV infection in men in a changing epidemic context — Systematic review and meta-analysis
INTRODUCTION: WHO/UNAIDS recommended Voluntary Medical Male Circumcision in 2007 based on systematic review of observational studies prior to 1999 and three randomized controlled trials (RCTs). To inform updated WHO guidance,...
Use of the multiplier method to estimate the size of populations most at risk of human immunodeficiency virus infection in China: A systematic review
OBJECTIVE: United Nations Programme on human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome and World Health Organization believe that some of the benchmark numbers collected may be inaccurate when using the multiplier...
HIV nonoccupational postexposure prophylaxis among men who have sex with men: A systematic review and meta-analysis of global data
HIV nonoccupational postexposure prophylaxis (nPEP) has been prescribed to men who have sex with men (MSM) for decades, but the global situation of nPEP implementation among this population remains unclear....
Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: A systematic review and meta-analysis
BACKGROUND: Talaromyces marneffei (TM) is a dimorphic fungus mainly prevalent in Southeast Asian countries, which often causes disseminated life-threatening infection. TM infection often occurs in HIV/AIDS patients even in the...
Differences in outcomes of chemoradiation in women with invasive cervical cancer by HIV status: A systematic review
PURPOSE: Cervical cancer is one of the leading causes of cancer death among women worldwide, and women living with human immunodeficiency virus (HIV) carry the highest burden of disease. Chemoradiation...
Childhood tuberculosis treatment outcome and its association with HIV co-infection in Ethiopia: A systematic review and meta-analysis
Background: Tuberculosis is the second leading cause of death from an infectious disease worldwide, next to HIV. Hence, initiating and determining the national tuberculosis treatment program and outcome is crucial....
Socio-demographic and ecological factors associated with anti-HCV prevalence in people who inject drugs: A systematic review
BACKGROUND: The World Health Organization (WHO) aim to eliminate hepatitis C virus (HCV) as a public health threat by 2030. People who inject drugs (PWID) are a key risk group...
The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: Scoping review
BACKGROUND: People living with HIV (PLHIV) are at a high risk of developing HPV-related cancers. HPV-related malignancies occur frequently and/or are high among PLHIV, with cervical cancer as a designated...
Effectiveness of interventions for changing HIV related risk behaviours among key populations in low-income setting: A meta-analysis, 2001-2016
The aim of this review was to conduct a meta-analysis to assess the effectiveness of behavioural interventions to reduce HIV-related risk behaviours among key populations: people who inject drugs, female...
