Category Archives: Epidemiology

Risk of colorectal cancer and associated mortality in HIV: A systematic review and meta-analysis

2017

BACKGROUND: As people with HIV live longer, the numbers of colorectal cancer cases are expected to increase. We sought to compare the colorectal cancer incidence and cause-specific mortality among people...

HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment

2016

OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...

Geographic distribution and temporal trends of HIV-1 subtypes through heterosexual transmission in China: A systematic review and meta-analysis

2017

Background: Heterosexual transmission (HST) has become the current predominant transmission pathways of the HIV-1 epidemic in China. The aim of this study was to explore the geographic and dynamic change...

Cancer risk factors among people living with HIV/AIDS in China: A systematic review and meta-analysis

2017

Cancer is a leading cause of death among people living with HIV/AIDS (PLWHA). We conducted a systematic review and meta-analysis to evaluate prevalence of cancer risk factors among Chinese PLWHA...

Does maternal HSV-2 coinfection increase mother-to-child transmission of HIV? A systematic review

2017

BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased...

Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: the Cresting Wave

2016

CONTEXT: South Africa has the most HIV infections of any country in the world, yet little is known about the adolescent continuum of care from HIV diagnosis through viral suppression....

Quantifying the harms and benefits from serosorting among HIV-negative gay and bisexual men: A systematic review and meta-analysis

2017

We conducted a systematic review and meta-analysis of the association between serosorting and HIV infection among HIV-negative men who have sex with men (MSM). Compared to no condomless anal sex...

Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: A systematic review and meta-analysis

2017

INTRODUCTION: To systematically review the literature on mother-to-child transmission in breastfed infants whose mothers received antiretroviral therapy and support the process of updating the World Health Organization infant feeding guidelines...

Incidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: A systematic review and meta-analysis

2017

OBJECTIVES: This systematic review aims to investigate the incidence and prevalence of type 2 diabetes mellitus (T2DM) in patients with HIV infection in African populations. SETTING: Only studies reporting data...

Factors associated with HIV testing and HIV treatment adherence: A systematic review

2017

BACKGROUND: The impact of the global economic crisis on HIV-related access and care remains unclear. The objective of this systematic review of the literature was to evaluate the association between...

Toxoplasma gondii infection in immunocompromised patients: A systematic review and meta-analysis

2017

Toxoplasma gondii has been suggested as an important opportunistic pathogen in immunocompromised patients. We conducted a global meta-analysis to assess the prevalence and odds ratios (ORs) of T. gondii infection...

Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data

2017

AIM: To investigate the relationship between vitamin D and liver fibrosis in hepatitis C-monoinfected or hepatitis C virus (HCV)-human immunodeficiency virus (HIV) co-infected patients. METHODS: Pertinent studies were located by...

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